{"id":"W4391260615","doi":"10.1111/tan.15355","title":"Establishing association between <i>HLA‐C*04:01</i> and severe <scp>COVID</scp>‐19","year":2024,"lang":"en","type":"letter","venue":"HLA","topic":"Immune responses and vaccinations","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; McGill University; McGill Genome Centre; Canada's Michael Smith Genome Sciences Centre","funders":"Canadian Institutes of Health Research; Government of Canada; Genome Canada","keywords":"Coronavirus disease 2019 (COVID-19); Association (psychology); Virology; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); 2019-20 coronavirus outbreak; Human leukocyte antigen; Medicine; Immunology; Psychology; Antigen; Internal medicine; Disease; Outbreak; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005718428,0.0002752054,0.0002038849,0.0007299588,0.0006843494,0.0006981842,0.0004009828,0.0009802632,0.00663954],"category_scores_gemma":[0.004091945,0.0001514541,0.0003213361,0.0008161783,0.0003906415,0.0004692703,0.0005024571,0.001438852,0.00125429],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002498537,"about_ca_system_score_gemma":0.0004135013,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002280358,"about_ca_topic_score_gemma":0.001579803,"domain_scores_codex":[0.9991703,0.000206209,0.00008003101,0.0002088063,0.0001748807,0.0001597533],"domain_scores_gemma":[0.9971775,0.0007029383,0.0008153434,0.0002628338,0.0005243652,0.00051709],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002039841,0.00004508589,0.9902542,0.00003412667,0.00004526386,0.001270904,0.00007867784,0.0000296938,0.0006607823,0.0001719233,0.003281741,0.003923666],"study_design_scores_gemma":[0.00002502157,0.0003622386,0.9697227,0.0001235929,0.0001041903,0.01624843,0.0006142404,0.0008033668,0.000703632,0.001059123,0.01021006,0.0000233337],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9764772,0.002314522,0.001536834,0.004300625,0.001019121,0.00006826433,0.002562305,0.00005747719,0.01166369],"genre_scores_gemma":[0.9950184,0.0005677844,0.0007949725,0.001138127,0.0007288416,0.00002083556,0.0009086771,0.00002015446,0.0008022367],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00663954,"threshold_uncertainty_score":0.02221149,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01529075020708877,"score_gpt":0.2488553844063661,"score_spread":0.2335646341992773,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}