{"id":"W4391260615","doi":"10.1111/tan.15355","title":"Establishing association between <i>HLA‐C*04:01</i> and severe <scp>COVID</scp>‐19","year":2024,"lang":"en","type":"letter","venue":"HLA","topic":"Immune responses and vaccinations","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; McGill University; McGill Genome Centre; Canada's Michael Smith Genome Sciences Centre","funders":"Canadian Institutes of Health Research; Government of Canada; Genome Canada","keywords":"Coronavirus disease 2019 (COVID-19); Association (psychology); Virology; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); 2019-20 coronavirus outbreak; Human leukocyte antigen; Medicine; Immunology; Psychology; Antigen; Internal medicine; Disease; Outbreak; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0006522603,0.0004041033,0.0005694032,0.0003265007,0.0004107546,0.0002740061,0.0003453646,0.002361731,0.0002283844],"category_scores_gemma":[0.001392002,0.0003902739,0.0002088502,0.0002694503,0.00005194936,0.0002105544,0.0002862971,0.002973054,0.001339102],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003562699,"about_ca_system_score_gemma":0.0002634362,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002490577,"about_ca_topic_score_gemma":0.00002102313,"domain_scores_codex":[0.9976614,0.0005083871,0.0004355319,0.0005960084,0.0001024751,0.0006961607],"domain_scores_gemma":[0.9959041,0.003263917,0.0003137007,0.0003887082,0.00009718077,0.00003241307],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000004284459,0.00001042127,0.00342366,0.0001855338,0.0004937486,0.00004987367,0.000587902,5.316483e-7,0.0007022527,0.00007391646,0.9934342,0.00103366],"study_design_scores_gemma":[0.0005458108,0.00005389407,0.003023405,0.0001129244,0.0004625577,0.0001046562,0.0001193479,9.236522e-7,0.0001967844,0.0004900254,0.9946998,0.000189808],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"other","genre_scores_codex":[0.07231484,0.08310611,0.0004227716,0.7748538,0.01472816,0.002280075,0.005534139,0.001728138,0.04503197],"genre_scores_gemma":[0.01473994,0.001253662,0.00008889895,0.2886392,0.003474267,0.0001065294,0.008114323,0.000216657,0.6833665],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.6383346,"threshold_uncertainty_score":0.9998549,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01529075020708877,"score_gpt":0.2488553844063661,"score_spread":0.2335646341992773,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}