{"id":"W4391283170","doi":"10.1210/jcemcr/luad174","title":"Remission of Ectopic Cushing Syndrome Secondary to Medullary Thyroid Cancer With Vandetanib and Selpercatinib","year":2024,"lang":"en","type":"article","venue":"JCEM Case Reports","topic":"Thyroid Cancer Diagnosis and Treatment","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Vandetanib; Medicine; Medullary thyroid cancer; Internal medicine; Tyrosine-kinase inhibitor; Thyroid; Cancer; Endocrinology; Hormone; Oncology; Cancer research; Thyroid cancer; Tyrosine kinase; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001547532,0.0001744821,0.0003664719,0.0001101338,0.00005436204,0.00002921484,0.00001380553,0.00006525878,0.000220714],"category_scores_gemma":[0.00002234542,0.0001172039,0.00006073667,0.0002060293,0.00002970683,0.00008285555,0.00003744687,0.0001524417,0.000002132376],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001463618,"about_ca_system_score_gemma":0.000366739,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006924469,"about_ca_topic_score_gemma":0.0002085994,"domain_scores_codex":[0.9987717,0.00001642823,0.0003447633,0.0004385765,0.0002460157,0.0001824618],"domain_scores_gemma":[0.9992141,0.00005771148,0.00008406685,0.0003353587,0.00006073223,0.0002480868],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0001445481,0.0002028626,0.03807667,0.001673583,0.0005696933,0.8883982,0.002078106,0.00002949311,0.01101788,0.00004231168,0.004629659,0.05313696],"study_design_scores_gemma":[0.001149616,0.001842265,0.04690716,0.004940968,0.0009253753,0.8871158,0.0004661993,0.00007163028,0.03215359,0.0001127779,0.02392766,0.0003869466],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9751411,0.0214987,0.00001967621,0.001091557,0.0002351094,0.0004683069,0.00001740655,0.00007383912,0.001454282],"genre_scores_gemma":[0.9977733,0.0006673395,0.000450905,0.0001828782,0.00008333389,0.0001099197,0.00001275715,0.00003471892,0.0006848418],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05275001,"threshold_uncertainty_score":0.4779436,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01133819362615252,"score_gpt":0.2886364151425337,"score_spread":0.2772982215163812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}