{"id":"W4391303528","doi":"10.1200/jco.2024.42.4_suppl.tps714","title":"MAIN-CAV: Phase III randomized trial of maintenance cabozantinib (CABO) and avelumab (Av) vs Av after first-line platinum-based chemotherapy in patients (pts) with metastatic urothelial cancer (mUC; Alliance A032001).","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Cabozantinib; Medicine; Urothelial cancer; Chemotherapy; Metastatic Urothelial Carcinoma; Avelumab; Oncology; Cancer; Internal medicine; Urothelial carcinoma; Bladder cancer; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001774906,0.002059311,0.002220542,0.0004053024,0.0003673771,0.001201887,0.001308429,0.001820236,0.01085607],"category_scores_gemma":[0.001512254,0.0007613784,0.001789598,0.0004418294,0.001148042,0.001105347,0.0005633896,0.003511547,0.00161675],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00107197,"about_ca_system_score_gemma":0.001510914,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001331814,"about_ca_topic_score_gemma":0.003380904,"domain_scores_codex":[0.9995539,0.0002178796,0.00002194432,0.00008805396,0.0000312848,0.00008697003],"domain_scores_gemma":[0.9990865,0.0001913939,0.0002044956,0.00006514497,0.0000507335,0.0004017343],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9819341,0.005093118,0.000516661,0.0003414372,0.0004076711,0.00002333561,0.00002568999,0.000271281,0.001980732,0.0001042581,0.001331097,0.007970628],"study_design_scores_gemma":[0.9407164,0.05637541,0.001160947,0.00002407511,0.0002609044,0.00003382276,0.00001483416,0.0003821157,0.0002552337,0.0001388914,0.0006300964,0.000007297098],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9765301,0.005399995,0.0007459827,0.001561396,0.0009470554,0.006529926,0.003378075,0.0003971634,0.004510374],"genre_scores_gemma":[0.9755713,0.002291408,0.002210626,0.001862098,0.0007010386,0.007077647,0.003681047,0.00007051674,0.006534265],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01085607,"threshold_uncertainty_score":0.03631717,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0465595784971834,"score_gpt":0.4148714997270794,"score_spread":0.368311921229896,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}