{"id":"W4391316762","doi":"10.1177/17407745231225470","title":"Research encouraging off-label use of quetiapine: A systematic meta-epidemiological analysis","year":2024,"lang":"en","type":"review","venue":"Clinical Trials","topic":"Pharmaceutical studies and practices","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Ethica (Canada)","funders":"","keywords":"Quetiapine; Medicine; Randomized controlled trial; Clinical trial; PsycINFO; Quetiapine Fumarate; MEDLINE; Off-label use; Psychiatry; Atypical antipsychotic; Antipsychotic; Internal medicine; Schizophrenia (object-oriented programming)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch","metaepi_broad"],"consensus_categories":[],"category_scores_codex":[0.0605962,0.002850831,0.01389461,0.01233404,0.0008473885,0.004809061,0.002466484,0.003429377,0.003280828],"category_scores_gemma":[0.1124114,0.002154869,0.05514276,0.01254498,0.001336069,0.002734382,0.002258981,0.002361105,0.0003209989],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00302561,"about_ca_system_score_gemma":0.005137836,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007754591,"about_ca_topic_score_gemma":0.01072074,"domain_scores_codex":[0.9409402,0.03463713,0.01471439,0.004762169,0.003961283,0.0009848528],"domain_scores_gemma":[0.8595094,0.1054698,0.02043222,0.006540492,0.007079573,0.0009684652],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"systematic_review","study_design_scores_codex":[0.002023234,0.0000309361,0.02188285,0.0878358,0.8820158,0.0001513328,0.0001165494,0.0003530035,0.0001685079,0.0001360826,0.0002702718,0.00501557],"study_design_scores_gemma":[0.0005339484,0.0001686965,0.009604041,0.009502929,0.9788954,0.00009264309,0.00006148971,0.0002895819,0.000110492,0.0001666051,0.0005529368,0.00002112506],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03202809,0.9615871,0.003236879,0.0005607809,0.0003849735,0.0007331389,0.0008503421,0.00008057901,0.0005380959],"genre_scores_gemma":[0.638964,0.349179,0.006649704,0.001217913,0.0003394267,0.001907422,0.001311811,0.00008100981,0.0003498084],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9861054,"threshold_uncertainty_score":0.3204672,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.9792123966898467,"score_gpt":0.780392014262269,"score_spread":0.1988203824275777,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}