{"id":"W4391323694","doi":"10.1007/s10528-023-10635-y","title":"A Comprehensive Metagenome Study Identifies Distinct Biological Pathways in Asthma Patients: An In-Silico Approach","year":2024,"lang":"en","type":"article","venue":"Biochemical Genetics","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Biology; Metagenomics; In silico; Microbiome; KEGG; Computational biology; Asthma; Human microbiome; Immunology; Genetics; Gene; Transcriptome; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001962532,0.0002876353,0.0003084226,0.0001256935,0.00004198053,0.00007017015,0.0003233618,0.0002915022,0.00001273028],"category_scores_gemma":[0.00004273208,0.0002507858,0.00009336495,0.0003059871,0.0001348267,0.000004905127,0.0002834544,0.0002506071,0.00001706019],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004978297,"about_ca_system_score_gemma":0.00008154163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003160611,"about_ca_topic_score_gemma":0.00004713521,"domain_scores_codex":[0.9978574,0.0001805718,0.0004802219,0.0008816717,0.0001486991,0.0004514337],"domain_scores_gemma":[0.9992858,0.00002148425,0.00004475343,0.0004303745,0.00007161202,0.0001459887],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00007545538,0.001463258,0.05875755,0.00008323868,0.00003280239,0.0000184902,0.0004345038,0.00001504534,0.9377249,0.00001959358,0.0002440853,0.001131047],"study_design_scores_gemma":[0.001996439,0.002238591,0.8856038,0.00005030018,0.0000290496,0.00001768329,0.001568975,0.0004001883,0.09758941,0.0001404774,0.009480439,0.0008846257],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934166,0.005437112,0.0000772783,0.00001624681,0.0001726518,0.0006504565,0.00007679809,0.00002861895,0.000124245],"genre_scores_gemma":[0.9980296,0.0002521416,0.0006167499,0.000104656,0.000157529,0.00006304682,0.0007154919,0.00003300214,0.00002775877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8401355,"threshold_uncertainty_score":0.9999945,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03835421797873151,"score_gpt":0.2886557408395842,"score_spread":0.2503015228608527,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}