{"id":"W4391328111","doi":"10.20944/preprints202401.1974.v1","title":"Transforming Growth Factor Beta and Alveolar Rhabdomyosarcoma: A Challenge of Tumor Differentiation and Chemotherapy Response","year":2024,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Sarcoma Diagnosis and Treatment","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"CancerCare Manitoba; McGill University; Research Institute in Oncology and Hematology; University of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"BETA (programming language); Alveolar rhabdomyosarcoma; Chemotherapy; Rhabdomyosarcoma; Cancer research; Transforming growth factor beta; Medicine; Oncology; Internal medicine; Transforming growth factor; Pathology; Sarcoma; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006408035,0.0001578916,0.0004173818,0.0002414339,0.0001031317,0.0007146237,0.0001468648,0.0003995508,0.001236898],"category_scores_gemma":[0.001001113,0.00006353703,0.0001875559,0.0002892461,0.0002851292,0.0004251559,0.0002126573,0.0009651516,0.0005901204],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006136582,"about_ca_system_score_gemma":0.0005802977,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000381696,"about_ca_topic_score_gemma":0.0005485631,"domain_scores_codex":[0.9997556,0.0000886296,0.00002398324,0.00002800985,0.00008409628,0.00001973918],"domain_scores_gemma":[0.9997018,0.0001308768,0.000057498,0.00001571743,0.00006457225,0.00002948632],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0006283208,0.0001241898,0.006634628,0.003000301,0.0002100859,0.0009739923,0.0003013287,0.001270876,0.03632874,0.01437659,0.03624068,0.8999102],"study_design_scores_gemma":[0.0001702744,0.0008762119,0.04423337,0.002645216,0.0003531619,0.009524599,0.001020439,0.002093196,0.03313733,0.02518387,0.8806916,0.0000705769],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.03989348,0.9182572,0.003428312,0.02621885,0.001086021,0.00002783838,0.0002230455,0.0001366964,0.01072869],"genre_scores_gemma":[0.3562996,0.6140928,0.007144756,0.005472545,0.002975302,0.0000890873,0.0005707084,0.0001619276,0.01319319],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001236898,"threshold_uncertainty_score":0.004452407,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07015150432129677,"score_gpt":0.3294588256234041,"score_spread":0.2593073213021073,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}