{"id":"W4391333047","doi":"10.1214/23-aap1969","title":"Toward a mathematical theory of trajectory inference","year":2024,"lang":"en","type":"article","venue":"The Annals of Applied Probability","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Mathematics; Inference; Trajectory; Applied mathematics; Mathematical economics; Calculus (dental); Artificial intelligence; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000858272,0.0001033404,0.0001702779,0.00001603372,0.00001996462,0.000009038398,0.0002416977,0.00008865176,0.00004831787],"category_scores_gemma":[0.00007451821,0.00006732943,0.0001276644,0.0000774305,0.0003357551,0.000001882197,0.00005395595,0.00009413153,0.000005145714],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002498665,"about_ca_system_score_gemma":0.00008205367,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003904746,"about_ca_topic_score_gemma":0.000002101313,"domain_scores_codex":[0.9992313,0.00005467996,0.0002644976,0.0002027786,0.0001143137,0.0001324148],"domain_scores_gemma":[0.9993802,0.000103908,0.00004403694,0.0003781486,0.00006222006,0.00003152046],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007197817,0.0003168657,0.0001107303,0.001150985,0.0001574221,4.731839e-7,0.001498879,0.0001333617,0.7917904,0.1853584,0.0002348837,0.01852779],"study_design_scores_gemma":[0.0000870516,0.0001314148,0.0003910551,0.00003211667,0.00002152642,0.000001044155,0.0000680857,0.0000798198,0.6786327,0.3197094,0.0007592091,0.00008656608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9834358,0.0006096644,0.00618771,0.0002026958,0.00004709256,0.0002749024,0.00002383907,0.00001650924,0.009201864],"genre_scores_gemma":[0.9991367,0.00006994342,0.0005740917,0.00009607436,0.0000459607,0.00002060243,0.000007491724,0.00001017061,0.00003891795],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1343509,"threshold_uncertainty_score":0.2745615,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1011774913481053,"score_gpt":0.309455018957174,"score_spread":0.2082775276090688,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}