{"id":"W4391341422","doi":"10.22541/au.170664051.11929717/v1","title":"Identification of predictive biomarkers of response to treatment in patients with antibody mediated rejection: a case –control proteomics study","year":2024,"lang":"en","type":"preprint","venue":"","topic":"Blood groups and transfusion","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Biomarker; Proteomics; Medicine; Urine; Antibody; Internal medicine; Quantitative proteomics; Biomarker discovery; Oncology; Immunology; Bioinformatics; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006405022,0.0002547984,0.0006335003,0.0006924242,0.00002024564,0.00001053242,0.00005549538,0.0001747275,0.0000143483],"category_scores_gemma":[0.00009372726,0.0001746259,0.00009687231,0.0005130008,0.00004385224,0.0000254413,0.00006567486,0.000217753,0.000002524891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002449588,"about_ca_system_score_gemma":0.0003091864,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001986073,"about_ca_topic_score_gemma":0.0005671352,"domain_scores_codex":[0.9979221,0.0002377993,0.0007740043,0.0005521166,0.0003810049,0.0001330383],"domain_scores_gemma":[0.9987037,0.000101193,0.0002246885,0.0005212332,0.0003545919,0.000094548],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1452184,0.01495489,0.7782156,0.001015769,0.003775149,0.001345345,0.01029218,0.0003311306,0.04307049,0.000005065905,0.000008257839,0.001767699],"study_design_scores_gemma":[0.01609409,0.01599167,0.9545252,0.0009261713,0.00195731,0.00004210893,0.001656887,0.001125262,0.007480622,0.00002127685,0.000001331414,0.0001780496],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9862269,0.00004989235,0.0009190909,0.0002005139,0.0001632179,0.0119159,0.0004440928,0.00004369579,0.00003671959],"genre_scores_gemma":[0.9989561,0.000008374067,0.0003161765,0.000007370641,0.00001784223,0.0005098546,0.00008611182,0.00003216477,0.00006596731],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1763096,"threshold_uncertainty_score":0.7121037,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007722785636848428,"score_gpt":0.2761111562873024,"score_spread":0.268388370650454,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}