{"id":"W4391358470","doi":"10.1111/cas.16096","title":"An engineered Accum‐E7 protein‐based vaccine with dual anti‐cervical cancer activity","year":2024,"lang":"en","type":"article","venue":"Cancer Science","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University; Department of National Defence; Université de Montréal","funders":"","keywords":"Medicine; Vaccination; Immune system; Cervical cancer; CD8; Immunology; Cancer; Adverse effect; CD19; Cancer research; Pharmacology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003818443,0.0002351914,0.0002548946,0.0002193487,0.0003707968,0.0001318567,0.000505734,0.0001307632,0.001364788],"category_scores_gemma":[0.00002578039,0.0001673157,0.00005480785,0.001011226,0.0005350474,0.0006884759,0.00004920016,0.0003803893,0.00007014078],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000176315,"about_ca_system_score_gemma":0.001597249,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006565141,"about_ca_topic_score_gemma":0.0001009013,"domain_scores_codex":[0.9984331,0.000107394,0.0001593003,0.0006011498,0.0001125082,0.0005866224],"domain_scores_gemma":[0.9992459,0.00006816034,0.00004921719,0.0004684574,0.0001214871,0.00004680506],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006583512,0.00008009763,0.0003968967,0.00003969689,0.00006028657,0.0000158638,0.0002717886,0.0002167854,0.9706475,0.000160795,0.0001668119,0.02728511],"study_design_scores_gemma":[0.0008434418,0.0004024017,0.02478319,0.000220298,0.00002648553,0.00003313234,0.00003651215,0.0008510461,0.9530873,0.000007368616,0.01941532,0.0002935025],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9811965,0.01442158,0.001365526,0.001201479,0.001109861,0.0003643625,0.000053498,0.0002015956,0.00008565958],"genre_scores_gemma":[0.998146,0.0001412278,0.00007734189,0.0002232737,0.00006868186,0.0002244835,0.000006543101,0.00002526983,0.001087182],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02699161,"threshold_uncertainty_score":0.9995481,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01394646936771313,"score_gpt":0.296133618963264,"score_spread":0.2821871495955508,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}