{"id":"W4391382741","doi":"10.7554/elife.89267.2.sa4","title":"Author Response: Optogenetic stimulation of the locus coeruleus enhances appetitive extinction in rats","year":2024,"lang":"en","type":"peer-review","venue":"","topic":"Photoreceptor and optogenetics research","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Optogenetics; Locus coeruleus; Neuroscience; Stimulation; Extinction (optical mineralogy); Psychology; Biology; Central nervous system; Paleontology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.0001965841,0.000860396,0.0006001061,0.0003859911,0.0003114833,0.0003657345,0.0006167452,0.001381667,0.1271002],"category_scores_gemma":[0.0003770154,0.0001718366,0.000381833,0.0001625077,0.000433922,0.0003043256,0.0004005242,0.001122857,0.02113554],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004579312,"about_ca_system_score_gemma":0.000320076,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006199746,"about_ca_topic_score_gemma":0.001101812,"domain_scores_codex":[0.9997292,0.00001679312,0.00001677398,0.00007925798,0.00008834162,0.00006964122],"domain_scores_gemma":[0.9996893,0.0000525197,0.00005537238,0.00002745893,0.00007272928,0.0001026165],"domain_codex":null,"domain_gemma":"evaluation","domain_candidate":"evaluation","domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003090062,0.0006635287,0.0016628,0.001002045,0.00008079272,0.001093617,0.000131958,0.0006616507,0.9071876,0.0008616066,0.02248865,0.06107578],"study_design_scores_gemma":[0.0006093908,0.004915069,0.05130636,0.0002912799,0.0001988238,0.002164107,0.0007266399,0.004301979,0.7370563,0.001161225,0.1971759,0.00009291317],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.719018,0.007796214,0.01546655,0.01630769,0.0107869,0.00129755,0.006408937,0.005108515,0.2178097],"genre_scores_gemma":[0.5741023,0.002298262,0.006078273,0.002413457,0.0007431373,0.0004540154,0.001859319,0.0004594198,0.4115918],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.9998034,"threshold_uncertainty_score":0.4251925,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08483491327750296,"score_gpt":0.4060600087866154,"score_spread":0.3212250955091124,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}