{"id":"W4391395352","doi":"10.22541/au.170667762.25200980/v1","title":"Beneficial Effects of novel Aureobasidium Pullulans strains produced Beta-1,3-1,6 Glucans on Interleukin-6 and D-Dimer levels in COVID-19 patients; results of a randomized multiple-arm pilot clinical study","year":2024,"lang":"en","type":"preprint","venue":"","topic":"Wound Healing and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital","funders":"","keywords":"Medicine; Aureobasidium pullulans; Coagulopathy; Internal medicine; Lymphocyte; Gastroenterology; Cytokine; Immune system; Erythrocyte sedimentation rate; Immunology; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006481193,0.0008580806,0.0013672,0.0002649101,0.0003952825,0.0003991425,0.0003805542,0.0006602845,0.001310332],"category_scores_gemma":[0.0005176184,0.0002944654,0.0005593739,0.000167062,0.0005025596,0.0004156899,0.000318721,0.001024624,0.0001848358],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002523212,"about_ca_system_score_gemma":0.0004141191,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001697079,"about_ca_topic_score_gemma":0.0003652474,"domain_scores_codex":[0.9997322,0.00009420893,0.00002784067,0.0000615614,0.00003658834,0.00004751968],"domain_scores_gemma":[0.9995545,0.00005304271,0.0001052089,0.00003276948,0.00002767347,0.0002268745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6849458,0.1151033,0.01664989,0.0006969423,0.0005611317,0.0007323285,0.0001569804,0.0004333794,0.1414899,0.00009085572,0.0004303824,0.03870923],"study_design_scores_gemma":[0.07579969,0.8860734,0.02542047,0.00003498201,0.0003286452,0.0004145255,0.0001115179,0.0004789573,0.0106656,0.00004923755,0.0006028173,0.00002023496],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990801,0.0004060747,0.00008402607,0.00002916975,0.00002422477,0.0002269814,0.00004790502,0.00000572614,0.00009590682],"genre_scores_gemma":[0.9979923,0.0003907973,0.000628289,0.00009960656,0.0000681954,0.000428863,0.0001528834,0.000003341291,0.0002357817],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0013672,"threshold_uncertainty_score":0.004383445,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1176546455684984,"score_gpt":0.4068470955549458,"score_spread":0.2891924499864474,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}