{"id":"W4391429432","doi":"10.1371/journal.pntd.0011865","title":"Unraveling the role of miRNAs as biomarkers in Chagas cardiomyopathy: Insights into molecular pathophysiology","year":2024,"lang":"en","type":"article","venue":"PLoS neglected tropical diseases","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"microRNA; Disease; Chagas disease; Cardiomyopathy; Bioinformatics; Medicine; Biomarker; Heart failure; Biology; Immunology; Pathology; Internal medicine; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008894251,0.0004742884,0.001414266,0.002084494,0.0002599499,0.0012759,0.0003886936,0.0008381043,0.001631352],"category_scores_gemma":[0.001820013,0.0002099894,0.000819267,0.00187951,0.0004241968,0.001502119,0.0004983339,0.0009701849,0.0005276811],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004456927,"about_ca_system_score_gemma":0.001706461,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004841506,"about_ca_topic_score_gemma":0.0007380191,"domain_scores_codex":[0.9996198,0.00008898197,0.0000874275,0.00006582397,0.0001120817,0.00002576507],"domain_scores_gemma":[0.9991329,0.0004860742,0.0001668505,0.00002081167,0.0001579267,0.00003545253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004676642,0.0001202558,0.009260776,0.08221976,0.001096947,0.002840662,0.0007656786,0.0008057612,0.0578401,0.01223669,0.01542897,0.8169168],"study_design_scores_gemma":[0.0001133668,0.0009580612,0.03734088,0.03022989,0.003188129,0.0159429,0.001169283,0.002487369,0.02321996,0.01951275,0.8656235,0.0002140157],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.00255336,0.9935645,0.001075347,0.00150482,0.0002089851,0.00001632038,0.000121607,0.00001800073,0.0009369678],"genre_scores_gemma":[0.0209168,0.9733942,0.003464669,0.001013847,0.0004331639,0.00004900352,0.0001643385,0.00000704741,0.0005569726],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002084494,"threshold_uncertainty_score":0.005457401,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007415834179825599,"score_gpt":0.2635283753815648,"score_spread":0.2561125412017392,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}