{"id":"W4391445529","doi":"10.1080/09546634.2024.2310633","title":"Ruxolitinib cream monotherapy demonstrates rapid improvement in the extent and signs of mild to moderate atopic dermatitis across head and neck and other anatomic regions in adolescents and adults: pooled results from 2 phase 3 studies","year":2024,"lang":"en","type":"article","venue":"Journal of Dermatological Treatment","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Innovaderm (Canada)","funders":"","keywords":"Ruxolitinib; Medicine; Atopic dermatitis; Tolerability; Janus kinase inhibitor; Eczema Area and Severity Index; Dermatology; Head and neck; Quality of life (healthcare); Internal medicine; Dupilumab; Janus kinase; Surgery; Adverse effect; Myelofibrosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001471726,0.0002146718,0.0006589799,0.0001205686,0.00006457233,0.0000448057,0.00005012957,0.00009303585,0.000002563566],"category_scores_gemma":[0.00006838247,0.0001178578,0.00006455613,0.0001010496,0.00022246,0.00008942362,0.00003277228,0.0001495413,3.352667e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004599979,"about_ca_system_score_gemma":0.00003850555,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008129973,"about_ca_topic_score_gemma":0.0001230034,"domain_scores_codex":[0.9985383,0.0001594389,0.0006965224,0.0002543276,0.0001330458,0.0002184296],"domain_scores_gemma":[0.9992406,0.0003050228,0.0001411779,0.0001179624,0.00004225885,0.0001529751],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.009538339,0.006326663,0.8659796,0.0009046223,0.001705587,0.007378292,0.03052073,0.00001520242,0.001085374,0.0002364864,0.0009131087,0.07539602],"study_design_scores_gemma":[0.04817834,0.004674227,0.9110314,0.006628914,0.0004860121,0.003760335,0.01455404,0.001298717,0.004787714,0.003708519,0.0005481323,0.0003436064],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9413122,0.05240964,0.00001320568,0.005535028,0.00003173004,0.0005199739,0.0001584031,0.000007596932,0.00001222962],"genre_scores_gemma":[0.9854855,0.01297626,0.0002035427,0.00126943,0.00001882823,0.00003009269,0.000004596131,0.000008161938,0.000003594684],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07505241,"threshold_uncertainty_score":0.48061,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04943712713521411,"score_gpt":0.3647427674632789,"score_spread":0.3153056403280648,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}