{"id":"W4391471691","doi":"10.7554/elife.91246","title":"ESCRT-III-dependent adhesive and mechanical changes are triggered by a mechanism detecting alteration of septate junction integrity in Drosophila epithelial cells","year":2024,"lang":"en","type":"article","venue":"eLife","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Child Health and Human Development; Directorate for Biological Sciences; Institute of Genetics; Fondation pour la Recherche Médicale; Fondation ARC pour la Recherche sur le Cancer; Agence Nationale de la Recherche","keywords":"Septate junctions; ESCRT; Cell biology; Drosophila (subgenus); Mechanism (biology); Septate; Biology; Anatomy; Botany; Genetics; Endosome; Gene; Intracellular; Gap junction","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005517724,0.0002404665,0.0001771702,0.0001426335,0.0001488673,0.0002303097,0.0002270079,0.0002720397,0.0007426193],"category_scores_gemma":[0.00005873044,0.0001483185,0.0002110639,0.00007039785,0.0002312521,0.0002269901,0.0002828937,0.000486638,0.000259031],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003640132,"about_ca_system_score_gemma":0.0001163235,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008014151,"about_ca_topic_score_gemma":0.001025815,"domain_scores_codex":[0.9999161,0.00000728141,0.000008450757,0.00002237299,0.00002345586,0.00002229769],"domain_scores_gemma":[0.9999303,0.000003438307,0.00002971448,0.000008835495,0.00000753239,0.00002023059],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002022626,0.000002074096,0.0001791931,0.00001139424,0.000002181114,0.00004070431,0.000004366721,0.00002523061,0.9993843,0.00006514165,0.00001253312,0.0002526866],"study_design_scores_gemma":[0.000007753614,0.00003098439,0.01805285,0.000004838789,0.000007464569,0.0002086202,0.00002933353,0.001044012,0.9793926,0.00005125157,0.001166124,0.000004276966],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948348,0.0007979725,0.002970357,0.0000726959,0.00001356751,0.00001091322,0.0003447126,0.00008603928,0.00086907],"genre_scores_gemma":[0.9956853,0.000277527,0.001458989,0.00004777518,0.000002694394,0.00001665897,0.0002806996,0.00002098886,0.002209307],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008014151,"threshold_uncertainty_score":0.002641141,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01226196607930786,"score_gpt":0.2489489165832211,"score_spread":0.2366869505039132,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}