{"id":"W4391483026","doi":"10.1016/j.canlet.2024.216661","title":"Immune checkpoints between epithelial-mesenchymal transition and autophagy: A conflicting triangle","year":2024,"lang":"en","type":"review","venue":"Cancer Letters","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"CancerCare Manitoba; Research Institute in Oncology and Hematology; University of Manitoba","funders":"CancerCare Manitoba Foundation","keywords":"Autophagy; Immune system; Biology; Epithelial–mesenchymal transition; Downregulation and upregulation; Cell biology; Cancer cell; Cancer research; Innate immune system; Immune checkpoint; Metastasis; Immunotherapy; Apoptosis; Cancer; Immunology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002424303,0.0004999597,0.001997782,0.0002474088,0.00008387109,0.00005728098,0.0001178393,0.0002876801,0.0002377996],"category_scores_gemma":[0.00001794783,0.0003883771,0.0007359611,0.0002921523,0.0001333726,0.00007597413,0.00003301424,0.0006559848,0.0001367723],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002456401,"about_ca_system_score_gemma":0.000333151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005327779,"about_ca_topic_score_gemma":6.306678e-7,"domain_scores_codex":[0.998057,0.00009937218,0.0006547016,0.0005747861,0.0002445457,0.0003695647],"domain_scores_gemma":[0.9991319,0.00008779859,0.0002110475,0.0003393399,0.00002504744,0.0002048281],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003742758,0.00002238399,0.000003385786,0.02283644,0.001708452,0.0004097436,0.0006290535,1.921165e-7,0.0003511574,0.00001556575,0.001404305,0.9725819],"study_design_scores_gemma":[0.001252327,0.00006766867,0.00008031636,0.02584396,0.008317267,0.0000934541,0.00001710999,0.0000079267,0.0002463452,0.00001604838,0.9636376,0.0004199709],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002485216,0.9930863,0.00005063561,0.00187894,0.0006242884,0.001064503,0.0004840696,0.0001701679,0.0001558636],"genre_scores_gemma":[0.0003964543,0.9944323,0.00003994717,0.001630256,0.00223381,0.0002932791,0.0003185247,0.0001266148,0.0005287931],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9721619,"threshold_uncertainty_score":0.9998568,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05084514827719955,"score_gpt":0.3873339671283306,"score_spread":0.336488818851131,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}