{"id":"W4391540851","doi":"10.3390/pharmaceutics16020227","title":"The Potential Use of Peptides in the Fight against Chagas Disease and Leishmaniasis","year":2024,"lang":"en","type":"article","venue":"Pharmaceutics","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Israel Science Foundation; International Development Research Centre","keywords":"Benznidazole; Leishmaniasis; Nifurtimox; Chagas disease; Miltefosine; Visceral leishmaniasis; Medicine; Tropical disease; Paromomycin; Trypanosomiasis; Disease; Trypanosoma cruzi; Pharmacology; Immunology; Biology; Internal medicine; Antibiotics; Microbiology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003464876,0.000442637,0.0004460138,0.0006151323,0.0002404199,0.0005950392,0.0003177489,0.000768755,0.001434593],"category_scores_gemma":[0.000272911,0.000134128,0.0003664846,0.0003198781,0.0003165866,0.0009363149,0.000456941,0.001226243,0.0007184196],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002046616,"about_ca_system_score_gemma":0.0002318442,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002232032,"about_ca_topic_score_gemma":0.0003342671,"domain_scores_codex":[0.999856,0.00003694231,0.00001193422,0.0000212418,0.00004581788,0.0000280529],"domain_scores_gemma":[0.9998901,0.0000313167,0.00002679827,0.000003861091,0.00002382487,0.00002404037],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0005320467,0.0004147781,0.001040618,0.01012256,0.000142202,0.001814476,0.0003331038,0.001517901,0.2724561,0.0130899,0.01503493,0.6835015],"study_design_scores_gemma":[0.0001148461,0.003501983,0.003464177,0.001347037,0.0001939803,0.007115151,0.0002499117,0.0009204533,0.08433037,0.004673445,0.8939955,0.00009324688],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01565009,0.9715859,0.003144837,0.001642182,0.000815681,0.00004240437,0.0000911287,0.00005876409,0.006969006],"genre_scores_gemma":[0.08832835,0.9005709,0.004235109,0.001562102,0.0008774103,0.00005960987,0.0001532222,0.00001367831,0.004199642],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001434593,"threshold_uncertainty_score":0.004799187,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08185342365292009,"score_gpt":0.3760537549155249,"score_spread":0.2942003312626048,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}