{"id":"W4391577449","doi":"10.1172/jci.insight.172312","title":"DDIT4L regulates mitochondrial and innate immune activities in early life","year":2024,"lang":"en","type":"article","venue":"JCI Insight","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's & Women's Health Centre of British Columbia; Université Laval; University of British Columbia; BC Children's Hospital","funders":"Natural Sciences and Engineering Research Council of Canada; Deutsche Forschungsgemeinschaft; Menzies School of Health Research; Canadian Cancer Society; BC Children's Hospital; Canadian Institutes of Health Research; Faculty of Medicine, University of British Columbia; Children's Hospital Foundation","keywords":"Innate immune system; Immune system; Biology; Inflammation; Cell biology; Immunology; U937 cell; Downregulation and upregulation; Myeloid; Monocyte; Cytokine; Fetus; Gene; Apoptosis; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000145212,0.0002792929,0.0001837592,0.0002743226,0.000177857,0.0003711014,0.0001639799,0.0002006838,0.0007883181],"category_scores_gemma":[0.000184403,0.0001122194,0.0001573167,0.0001163699,0.0002754007,0.0001414472,0.0002548757,0.0002825756,0.0002281379],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004717618,"about_ca_system_score_gemma":0.0002730555,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006351661,"about_ca_topic_score_gemma":0.0009996502,"domain_scores_codex":[0.999873,0.00002382665,0.00001251731,0.00002653511,0.00002792022,0.00003617648],"domain_scores_gemma":[0.9998761,0.00001156664,0.00005885433,0.000009108676,0.00001452816,0.00002974046],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000325129,0.00001235601,0.002467043,0.00003333645,0.000005175573,0.0001609007,0.00003468721,0.00009771963,0.9938486,0.000217303,0.00006031538,0.002737414],"study_design_scores_gemma":[0.000026549,0.000302021,0.05861044,0.00002730334,0.00003967457,0.0007274844,0.0002209464,0.001229876,0.9327177,0.0002743865,0.005812645,0.00001094526],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926697,0.00309148,0.00224585,0.0001885492,0.00002853027,0.000008317427,0.0005069426,0.00008885613,0.001171755],"genre_scores_gemma":[0.9954029,0.001197576,0.000873651,0.00005526182,0.00001013918,0.00001711248,0.0004236281,0.00001747722,0.002002192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007883181,"threshold_uncertainty_score":0.003422856,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03269888505155352,"score_gpt":0.3364816093234284,"score_spread":0.3037827242718749,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}