{"id":"W4391597419","doi":"10.1001/jama.2024.0572","title":"Endovascular Thrombectomy for Large Ischemic Stroke Across Ischemic Injury and Penumbra Profiles","year":2024,"lang":"en","type":"article","venue":"JAMA","topic":"Acute Ischemic Stroke Management","field":"Medicine","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; St. Michael's Hospital; Toronto Western Hospital","funders":"","keywords":"Medicine; Penumbra; Randomized controlled trial; Stroke (engine); Internal medicine; Cardiology; Perfusion scanning; Ischemic stroke; Ischemia; Perfusion","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002653531,0.0003507628,0.0009574385,0.0003785258,0.0001554189,0.0006506107,0.0002691905,0.0003690402,0.00143298],"category_scores_gemma":[0.003042003,0.0001114944,0.0007447784,0.0004809079,0.0003651584,0.000496942,0.000416323,0.0004715491,0.0001348523],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002026499,"about_ca_system_score_gemma":0.0003475753,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002860012,"about_ca_topic_score_gemma":0.001022516,"domain_scores_codex":[0.9985729,0.0009338855,0.00013879,0.0001085182,0.0001353984,0.000110479],"domain_scores_gemma":[0.9983075,0.0006729647,0.0006510917,0.00008429124,0.000048224,0.0002359585],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.2550567,0.003556021,0.4911922,0.00213243,0.01044704,0.0003248122,0.0002200884,0.002167565,0.004762636,0.001005121,0.002161359,0.226974],"study_design_scores_gemma":[0.04694091,0.09562447,0.8339955,0.0008066345,0.007118799,0.00168046,0.0005750777,0.003605021,0.00286862,0.002608646,0.004115423,0.00006058691],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930001,0.005017739,0.0004372134,0.0002694485,0.00003583436,0.0001411481,0.0002208191,0.000008233009,0.0008693999],"genre_scores_gemma":[0.9980551,0.0008959566,0.0002925573,0.000231941,0.0001139572,0.00007473618,0.0001962823,0.000001537486,0.0001378632],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002653531,"threshold_uncertainty_score":0.01403332,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01179404057386295,"score_gpt":0.2964792526506365,"score_spread":0.2846852120767735,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}