{"id":"W4391610494","doi":"10.1111/imm.13758","title":"Chromatin‐binding deubiquitinase <scp>MYSM1</scp> acts in haematopoietic progenitors to control dendritic cell development and to program dendritic cell responses to microbial stimulation","year":2024,"lang":"en","type":"article","venue":"Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill Genome Centre; McGill University; McGill University Health Centre","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Leukemia and Lymphoma Society of Canada; McGill University","keywords":"Dendritic cell; Cell biology; Progenitor cell; Chromatin; Haematopoiesis; Cell; Stimulation; Biology; Chemistry; Stem cell; Immunology; Immune system; Biochemistry; DNA; Neuroscience","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000132859,0.0002372604,0.0001487687,0.0002554671,0.0002179482,0.0003369422,0.0002684224,0.0002664593,0.001852093],"category_scores_gemma":[0.00008934508,0.0001583077,0.0002056541,0.0001378054,0.0003540564,0.0002408042,0.0002629153,0.0004377309,0.0005682316],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003773326,"about_ca_system_score_gemma":0.0001827581,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004851435,"about_ca_topic_score_gemma":0.0009171011,"domain_scores_codex":[0.9998499,0.00001357205,0.00001218425,0.00005061351,0.00004463177,0.00002915384],"domain_scores_gemma":[0.9998708,0.00001018193,0.00004790482,0.00002077447,0.00001206075,0.00003834905],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004196975,0.000005244531,0.000500169,0.00002717252,0.000002993883,0.0000433571,0.000005234607,0.00005723852,0.9981178,0.0001889825,0.00005740016,0.0009524391],"study_design_scores_gemma":[0.000007050466,0.00006619035,0.01333982,0.00000620837,0.00001006757,0.0003838284,0.00002151379,0.001166952,0.9806793,0.00007397268,0.004240305,0.000004937048],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871502,0.00242561,0.005887345,0.0001393552,0.0000393636,0.00002669048,0.001299542,0.0002432474,0.002788615],"genre_scores_gemma":[0.9937504,0.0004438377,0.001733982,0.0000591454,0.000006919861,0.00001779947,0.0006730318,0.00002887461,0.003286057],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001852093,"threshold_uncertainty_score":0.006195903,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01064275626378015,"score_gpt":0.2612615196650245,"score_spread":0.2506187634012443,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}