{"id":"W4391651983","doi":"10.1111/all.16049","title":"Immunotherapeutic effects of specific and nonspecific mRNA‐lipid nanoparticles in a mouse model of HDM‐induced airway inflammation","year":2024,"lang":"en","type":"letter","venue":"Allergy","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Acuitas Therapeutics (Canada)","funders":"","keywords":"Inflammation; Immunology; Messenger RNA; Airway; Medicine; Chemistry; Biochemistry; Surgery; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000126562,0.0002763715,0.0004932148,0.0004292328,0.0000376903,0.000015717,0.0001523093,0.0007307825,0.000226771],"category_scores_gemma":[0.00001829807,0.0002592773,0.0001323022,0.0001295718,0.0001266129,0.0001096657,0.00006218746,0.0009089418,0.0001489984],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000635803,"about_ca_system_score_gemma":0.00004768035,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009693651,"about_ca_topic_score_gemma":0.00002301883,"domain_scores_codex":[0.9984877,0.0002062233,0.0006463789,0.000339438,0.00006071739,0.0002595801],"domain_scores_gemma":[0.9990799,0.0002027715,0.0002823774,0.0003565882,0.00007084874,0.000007543858],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001566572,0.00005041357,0.000003245505,0.0002974205,0.0002873398,0.000005580989,0.0006650509,0.00005367328,0.9324383,0.0001273744,0.06326836,0.00264665],"study_design_scores_gemma":[0.0008088663,0.0001731952,0.00003109725,0.0002518872,0.00002875069,0.00001189016,0.00004309151,0.0001235299,0.7321985,0.00005689703,0.2660857,0.0001865695],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9626933,0.01219179,0.00009648053,0.01816586,0.005191576,0.0006530405,0.00001759965,0.0000891227,0.0009011754],"genre_scores_gemma":[0.9530215,0.004792992,0.00005313612,0.009979139,0.0003528786,0.0001122017,0.0004544237,0.0001337023,0.03109998],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2028173,"threshold_uncertainty_score":0.9999859,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0159773742574906,"score_gpt":0.2154577671936737,"score_spread":0.1994803929361831,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}