{"id":"W4391694888","doi":"10.1016/j.celrep.2024.113750","title":"Vibrio cholerae arrests intestinal epithelial proliferation through T6SS-dependent activation of the bone morphogenetic protein pathway","year":2024,"lang":"en","type":"article","venue":"Cell Reports","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Vibrio cholerae; Microbiology; Bone morphogenetic protein; Biology; Cell biology; Bone morphogenetic protein 2; Bacteria; Genetics; In vitro; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000978506,0.0002483684,0.0001395756,0.0001361856,0.0001024905,0.000222736,0.000122345,0.0001798514,0.0009308446],"category_scores_gemma":[0.00008184507,0.000101506,0.0002065948,0.00006332574,0.0002311437,0.00009485464,0.0002084068,0.0004414294,0.0003150612],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003271165,"about_ca_system_score_gemma":0.0003207362,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001757384,"about_ca_topic_score_gemma":0.0025417,"domain_scores_codex":[0.9998962,0.00001597947,0.000007142974,0.00001089354,0.00003226274,0.00003749867],"domain_scores_gemma":[0.9999458,0.000007524551,0.0000136445,0.000006348029,0.000008553358,0.00001818055],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004254606,0.00001028711,0.00008268812,0.00001758763,0.000001257837,0.00001829227,0.000006248181,0.00003520578,0.9993688,0.00005853219,0.00003518782,0.0003232453],"study_design_scores_gemma":[0.00002086951,0.0002296158,0.006436781,0.00001006553,0.000005684666,0.00008517145,0.00006380343,0.001029367,0.9889424,0.00007167007,0.003100715,0.000003865689],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919552,0.001914773,0.001905576,0.0002755738,0.00004922095,0.0000254555,0.0003728447,0.00008151463,0.003419743],"genre_scores_gemma":[0.9924312,0.00102598,0.0009595603,0.00007401396,0.000008871537,0.00002956652,0.0003105747,0.00001205933,0.005148141],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001757384,"threshold_uncertainty_score":0.003494322,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01222711619907026,"score_gpt":0.2512572654498724,"score_spread":0.2390301492508021,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}