{"id":"W4391708335","doi":"10.1101/2024.02.05.578945","title":"The Guinea Pig: A New Model for Human Preimplantation Development","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Université de Montréal; Vetenskapsrådet; Svenska Sällskapet för Medicinsk Forskning","keywords":"Blastocyst; Biology; Embryo; Embryogenesis; Inner cell mass; Offspring; Cell biology; Computational biology; Genetics; Evolutionary biology; Pregnancy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009723442,0.0005327579,0.0003988167,0.0006942638,0.0003871296,0.0006045903,0.0006448007,0.0008244432,0.007251736],"category_scores_gemma":[0.0003553388,0.0003223671,0.0003839973,0.0002670924,0.0007117406,0.0006549669,0.0007615801,0.001495149,0.001587226],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002463496,"about_ca_system_score_gemma":0.0003346871,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006226992,"about_ca_topic_score_gemma":0.0009568485,"domain_scores_codex":[0.9997301,0.0001011955,0.00001607067,0.00006402183,0.00006379802,0.00002484375],"domain_scores_gemma":[0.9997305,0.00008330903,0.00003776397,0.00006824789,0.0000301319,0.00004996085],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006463957,0.0002291738,0.001343864,0.0003583588,0.00005352003,0.001002958,0.0001940754,0.0003337841,0.9522834,0.01258606,0.003632648,0.02733587],"study_design_scores_gemma":[0.0003250533,0.005325705,0.0174162,0.0006869984,0.0003443708,0.01730143,0.0004160443,0.004121416,0.5309703,0.008518223,0.4144479,0.0001263751],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4730663,0.04001735,0.3901984,0.007426545,0.005085212,0.001849437,0.008309851,0.002792781,0.07125413],"genre_scores_gemma":[0.6578427,0.02063667,0.2592725,0.00204452,0.0003629477,0.002268494,0.005533159,0.0007191012,0.05131998],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007251736,"threshold_uncertainty_score":0.02425951,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02680713673833128,"score_gpt":0.2742854961331118,"score_spread":0.2474783593947805,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}