{"id":"W4391755866","doi":"10.1245/s10434-024-15013-5","title":"Early Onset Intrahepatic Cholangiocarcinoma: Clinical Characteristics, Oncological Outcomes, and Genomic/Transcriptomic Features","year":2024,"lang":"en","type":"article","venue":"Annals of Surgical Oncology","topic":"Cholangiocarcinoma and Gallbladder Cancer Studies","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Intrahepatic Cholangiocarcinoma; Medicine; Cohort; Surgical oncology; Internal medicine; CDKN2A; Oncology; Cancer; Transcriptome; Gastroenterology; Gene; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002797793,0.0001864217,0.0002391887,0.0007565771,0.0002133393,0.0005038276,0.0001603119,0.000194877,0.001093218],"category_scores_gemma":[0.0007196973,0.0001002741,0.0001985451,0.001446498,0.0001797213,0.0002235971,0.000335754,0.0001662016,0.0001803505],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002176046,"about_ca_system_score_gemma":0.000237563,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001940464,"about_ca_topic_score_gemma":0.00349822,"domain_scores_codex":[0.9998652,0.00001725365,0.00001869172,0.00004296643,0.00002632901,0.0000295326],"domain_scores_gemma":[0.9991705,0.0001098542,0.0004482799,0.00005403099,0.00008584962,0.0001314259],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001155402,0.000008632497,0.9975248,0.0000172792,0.00002334024,0.00009081906,0.00001853487,0.0000293131,0.0009283097,0.000007434307,0.00006275369,0.001173229],"study_design_scores_gemma":[0.000002536754,0.00001801259,0.9992823,0.000003861217,0.00001666484,0.0003505904,0.00003422587,0.0000472916,0.0001169581,0.00001182503,0.0001143711,0.000001385463],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979841,0.0004459777,0.00009498103,0.00002282886,0.000002305112,0.000004588567,0.001140946,0.000005100138,0.00029923],"genre_scores_gemma":[0.9979935,0.00018402,0.0001094871,0.00001330392,0.000006572568,0.000006507348,0.001598981,0.000001774293,0.00008599983],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001940464,"threshold_uncertainty_score":0.003858387,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08474093261457946,"score_gpt":0.3991867256338319,"score_spread":0.3144457930192525,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}