{"id":"W4391756195","doi":"10.1016/j.jdin.2023.11.015","title":"Characterization of disease burden, treatment and comorbidities in a large, real-world cohort of patients with atopic dermatitis: The CorEvitas Atopic Dermatitis Registry","year":2024,"lang":"en","type":"article","venue":"JAAD International","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Probity Medical Research; Queen's University","funders":"Janssen Pharmaceuticals; Chugai Pharmaceutical; Feinberg School of Medicine; Genentech; LG Chem; Medac; Bausch Health; Galderma; Alberta Innovates Bio Solutions; Sanofi; Kyowa Hakko Kirin; Celgene; BioCryst; Queen's University; Northwestern University; Pfizer; Incyte; Glenmark Pharmaceuticals; EQRx; Kyowa Kirin Pharmaceutical Development; Scheme for Promotion of Academic and Research Collaboration; Sun Pharma; Dermira; Les Laboratories Pierre Fabre; Valeant Pharmaceuticals International; Regeneron Pharmaceuticals; George Washington University; Daiichi Sankyo Europe; LEO Pharma; Ortho Dermatologics; Gilead Sciences; Yale University; Amgen; Eli Lilly and Company; Bristol-Myers Squibb; GlaxoSmithKline","keywords":"Atopic dermatitis; Medicine; Dermatology; Cohort; Disease; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003576166,0.00009173111,0.0001837441,0.0001151384,0.00002359329,0.0000153251,0.00006033412,0.00002681778,0.0001700012],"category_scores_gemma":[0.00002852916,0.00006105919,0.00004137439,0.00008995267,0.0001168083,0.0001119027,0.00002358978,0.00005439718,0.000002861633],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005455724,"about_ca_system_score_gemma":0.00008544631,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008185949,"about_ca_topic_score_gemma":0.00008892801,"domain_scores_codex":[0.9993228,0.00003639004,0.000259853,0.0001227839,0.0001787739,0.00007944223],"domain_scores_gemma":[0.9995755,0.00006737922,0.00009218636,0.0001352157,0.00008551657,0.00004422706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00003271993,0.0001557533,0.9948186,0.0002662554,0.0001679667,0.00004861427,0.0003177301,9.84756e-7,0.000009192863,0.002772437,0.0007869744,0.0006228141],"study_design_scores_gemma":[0.0008905962,0.00003509539,0.9915013,0.0005618019,0.0001141268,0.00001074662,0.00004367358,0.0003859205,0.000150482,0.0001784109,0.00607645,0.00005142447],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955289,0.0004148526,0.00003602615,0.001753943,0.0001530201,0.0003192873,0.0004548967,0.00001660252,0.001322413],"genre_scores_gemma":[0.9973126,0.0005840528,0.00001795221,0.0001999427,0.00004831856,0.0000601111,0.0009843603,0.00000795101,0.0007847229],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005289475,"threshold_uncertainty_score":0.2489921,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00865967817964794,"score_gpt":0.2606343049792871,"score_spread":0.2519746267996392,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}