{"id":"W4391756195","doi":"10.1016/j.jdin.2023.11.015","title":"Characterization of disease burden, treatment and comorbidities in a large, real-world cohort of patients with atopic dermatitis: The CorEvitas Atopic Dermatitis Registry","year":2024,"lang":"en","type":"article","venue":"JAAD International","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Probity Medical Research; Queen's University","funders":"Janssen Pharmaceuticals; Chugai Pharmaceutical; Feinberg School of Medicine; Genentech; LG Chem; Medac; Bausch Health; Galderma; Alberta Innovates Bio Solutions; Sanofi; Kyowa Hakko Kirin; Celgene; BioCryst; Queen's University; Northwestern University; Pfizer; Incyte; Glenmark Pharmaceuticals; EQRx; Kyowa Kirin Pharmaceutical Development; Scheme for Promotion of Academic and Research Collaboration; Sun Pharma; Dermira; Les Laboratories Pierre Fabre; Valeant Pharmaceuticals International; Regeneron Pharmaceuticals; George Washington University; Daiichi Sankyo Europe; LEO Pharma; Ortho Dermatologics; Gilead Sciences; Yale University; Amgen; Eli Lilly and Company; Bristol-Myers Squibb; GlaxoSmithKline","keywords":"Atopic dermatitis; Medicine; Dermatology; Cohort; Disease; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00343381,0.0001581998,0.000417416,0.00138595,0.0004263849,0.001157891,0.0007789124,0.0007770538,0.001752738],"category_scores_gemma":[0.01355225,0.0002355965,0.0003117224,0.001977796,0.0002826055,0.001068501,0.0007493332,0.0008987889,0.000342175],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003704368,"about_ca_system_score_gemma":0.0006937079,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002339493,"about_ca_topic_score_gemma":0.003162413,"domain_scores_codex":[0.9978999,0.000638678,0.0004904916,0.0003696445,0.0004596202,0.0001416139],"domain_scores_gemma":[0.9857275,0.00487343,0.0051066,0.001472801,0.001838024,0.0009815533],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002530932,0.00005255075,0.971584,0.0001082242,0.0001559273,0.0002087704,0.00009735892,0.00008438224,0.0001754927,0.0001961961,0.0188232,0.008260633],"study_design_scores_gemma":[0.00009586255,0.0001569549,0.9807442,0.000236006,0.0002132503,0.002377128,0.0005045037,0.001244613,0.000225685,0.0003453236,0.01381995,0.00003664696],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9569817,0.005051075,0.0007981009,0.01272096,0.0006826249,0.0001020037,0.02072614,0.00005718421,0.00288006],"genre_scores_gemma":[0.9817354,0.001608393,0.001231446,0.002841166,0.001803708,0.000121263,0.01015225,0.00002877378,0.0004776287],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00343381,"threshold_uncertainty_score":0.01815993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00865967817964794,"score_gpt":0.2606343049792871,"score_spread":0.2519746267996392,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}