{"id":"W4391773493","doi":"10.1038/s41574-024-00951-7","title":"Obesity and the kidney: mechanistic links and therapeutic advances","year":2024,"lang":"en","type":"review","venue":"Nature Reviews Endocrinology","topic":"Apelin-related biomedical research","field":"Medicine","cited_by":73,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto East General Hospital; Toronto General Hospital; University of Toronto","funders":"","keywords":"Kidney disease; Metformin; Medicine; Diabetes mellitus; Obesity; Kidney; Renal function; Incretin; Internal medicine; Regulator; Weight loss; Endocrinology; Bioinformatics; Type 2 diabetes; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001114528,0.001022239,0.002006267,0.001587146,0.0002894966,0.001909212,0.001204881,0.001854968,0.004504089],"category_scores_gemma":[0.001435125,0.0002753812,0.0005595664,0.001928126,0.0007923462,0.001691924,0.001259944,0.0035702,0.001779234],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000759663,"about_ca_system_score_gemma":0.001634442,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000855176,"about_ca_topic_score_gemma":0.001979658,"domain_scores_codex":[0.9997558,0.00004647221,0.00002791657,0.00004173416,0.00009444144,0.0000336989],"domain_scores_gemma":[0.9993653,0.0003311146,0.00006536169,0.00001786092,0.0001348247,0.00008554375],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002938244,0.0001174453,0.0001930784,0.01433163,0.0001815062,0.0002054635,0.00004519464,0.0005413712,0.001884056,0.008223147,0.06081032,0.913173],"study_design_scores_gemma":[0.00007257387,0.0001155655,0.0007368352,0.003849438,0.000177613,0.0005275799,0.00007694757,0.0001320457,0.0003220991,0.005748193,0.9882131,0.00002796867],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003954355,0.9986309,0.00006895274,0.0005380037,0.0003306154,0.000001486581,0.00001163109,0.000005109316,0.0003737489],"genre_scores_gemma":[0.0003011249,0.998544,0.00008985176,0.0003268564,0.0004712666,0.000002678613,0.00001643676,8.597524e-7,0.0002469055],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004504089,"threshold_uncertainty_score":0.01506764,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0423131544851084,"score_gpt":0.4196801339623398,"score_spread":0.3773669794772314,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}