{"id":"W4391809075","doi":"10.1101/2024.02.11.24302530","title":"Phase II/III Double-Blind Study Evaluating Safety and Immunogenicity of a Single Intramuscular Booster Dose of the Recombinant SARS-CoV-2 Vaccine “Patria” (AVX/COVID-12) Using an Active Newcastle Disease Viral Vector (NDV) during the Omicron Outbreak in Healthy Adults with Elevated Baseline Antibody Titers from Prior COVID-19 and/or SARS-CoV-2 Vaccination","year":2024,"lang":"en","type":"preprint","venue":"medRxiv","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nuclear Waste Management Organization","funders":"","keywords":"Immunogenicity; Virology; Medicine; Booster dose; Titer; Newcastle disease; Antibody; Booster (rocketry); Immunology; Virus; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002144589,0.001868334,0.002407693,0.0003962476,0.0005968053,0.0007612522,0.0009368512,0.001686821,0.003669255],"category_scores_gemma":[0.001058767,0.0007563063,0.001068324,0.0003111926,0.001697799,0.0009472427,0.0003167647,0.003283458,0.0009777527],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005668238,"about_ca_system_score_gemma":0.001451018,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000397197,"about_ca_topic_score_gemma":0.000648431,"domain_scores_codex":[0.999353,0.000228903,0.00004960146,0.0001816952,0.00005698052,0.000129897],"domain_scores_gemma":[0.9988773,0.0001819355,0.0002055639,0.000171816,0.0001407855,0.0004226419],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7956111,0.1399872,0.001207603,0.0003682297,0.0003596674,0.0000580733,0.0001179794,0.0006679623,0.04570988,0.0001057163,0.0007783719,0.01502821],"study_design_scores_gemma":[0.2666201,0.7243741,0.00220808,0.00001193473,0.0001685632,0.00003855727,0.00002729167,0.0005737228,0.005226172,0.0001139551,0.0006213387,0.00001619668],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991778,0.0005686202,0.00104726,0.0001224715,0.0002848503,0.004863101,0.0004546299,0.00008318348,0.0007979722],"genre_scores_gemma":[0.9842581,0.000568075,0.002230318,0.0004970229,0.0002940581,0.008308895,0.0008930685,0.00002988939,0.002920625],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003669255,"threshold_uncertainty_score":0.01227492,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.100673764141423,"score_gpt":0.4214180685397295,"score_spread":0.3207443043983065,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}