{"id":"W4391810436","doi":"10.3390/siuj5010006","title":"“Pass the Genetic Scalpel”: A Comprehensive Review of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) in Urological Cancers","year":2024,"lang":"en","type":"review","venue":"Société Internationale d’Urologie Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"CRISPR; PTEN; Prostate cancer; Medicine; Bladder cancer; Cancer research; Cancer; Oncology; Bioinformatics; Internal medicine; Biology; PI3K/AKT/mTOR pathway; Gene; Apoptosis; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001717398,0.0009754624,0.002635518,0.007242254,0.0003562817,0.001121554,0.001187795,0.001240535,0.003316897],"category_scores_gemma":[0.003184462,0.0003958843,0.002033002,0.005528664,0.0005568389,0.00146453,0.0007688481,0.001048643,0.0005829294],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009644415,"about_ca_system_score_gemma":0.00319551,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003113633,"about_ca_topic_score_gemma":0.005412028,"domain_scores_codex":[0.999246,0.0001817355,0.000254944,0.00008683155,0.0001909454,0.00003959584],"domain_scores_gemma":[0.9971848,0.00216931,0.0002997278,0.00003488197,0.0002539745,0.00005723385],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001231137,0.00004768829,0.000284233,0.373331,0.00073196,0.000218297,0.0002010611,0.0003011152,0.001089751,0.001656982,0.0196001,0.6024148],"study_design_scores_gemma":[0.00008411485,0.0004860412,0.003567879,0.2587675,0.004711758,0.00261298,0.0003682078,0.0002076047,0.0009105311,0.001785652,0.7264098,0.0000879494],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000945529,0.9993705,0.0000640705,0.0001390971,0.00006177126,0.00001041304,0.0000352753,0.000004357853,0.0002199767],"genre_scores_gemma":[0.0005629186,0.9988513,0.000217017,0.0001954485,0.00003816954,0.00001563818,0.00004217009,0.000001766262,0.00007559638],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.007242254,"threshold_uncertainty_score":0.01109618,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05026840380366124,"score_gpt":0.414021065872569,"score_spread":0.3637526620689078,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}