{"id":"W4391815232","doi":"10.1016/j.talanta.2024.125762","title":"Lipid organization and turnover in the plasma membrane of human differentiating neural progenitor cells revealed by time-of-flight secondary ion mass spectrometry imaging","year":2024,"lang":"en","type":"article","venue":"Talanta","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Hasselbladstiftelsen; Vetenskapsrådet","keywords":"Chemistry; Lipidomics; Cell biology; Membrane; Biochemistry; Neurodegeneration; Membrane fluidity; Membrane lipids; Biophysics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001660858,0.0002286701,0.0001529046,0.0004466852,0.0001592894,0.0001877663,0.0001594752,0.0002351098,0.0004030827],"category_scores_gemma":[0.0001663683,0.0001099698,0.0001609014,0.0003113939,0.0001360382,0.0002087119,0.0001564022,0.0002402726,0.0001896713],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001839499,"about_ca_system_score_gemma":0.0001649334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001120211,"about_ca_topic_score_gemma":0.0007666123,"domain_scores_codex":[0.999947,0.000005374187,0.000004197301,0.00001475555,0.00002037112,0.000008399298],"domain_scores_gemma":[0.9999311,0.00001162393,0.00001682698,0.000004621689,0.00002750662,0.000008323317],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005576479,0.00000388794,0.0008638775,0.00002119213,0.000002625053,0.00007002188,0.00003613083,0.00004823928,0.9970509,0.00003581607,0.00001669672,0.001794857],"study_design_scores_gemma":[0.000004332298,0.00008285147,0.02026137,0.000007337032,0.00001972549,0.000623563,0.000115713,0.003332976,0.9743122,0.00009910247,0.001130481,0.00001040034],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902171,0.0009868687,0.007413603,0.00004315257,0.000007857469,0.00001553417,0.0005835284,0.00006761488,0.0006647032],"genre_scores_gemma":[0.973878,0.002134119,0.02134404,0.00006078339,0.00001165212,0.00006325816,0.001037958,0.00003669917,0.001433557],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001120211,"threshold_uncertainty_score":0.002227366,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003554681568165362,"score_gpt":0.2144275981653009,"score_spread":0.2108729165971355,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}