{"id":"W4391823908","doi":"10.1164/rccm.202310-1895oc","title":"Limiting Overdistention or Collapse When Mechanically Ventilating Injured Lungs: A Randomized Study in a Porcine Model","year":2024,"lang":"en","type":"article","venue":"American Journal of Respiratory and Critical Care Medicine","topic":"Respiratory Support and Mechanisms","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Ottawa Hospital; SickKids Foundation; Hospital for Sick Children; St. Michael's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Medicine; ARDS; Transpulmonary pressure; Positive end-expiratory pressure; Cardiology; Lung; Respiratory physiology; Mechanical ventilation; Anesthesia; Internal medicine; Lung volumes","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003011359,0.0002925051,0.001661582,0.0005964769,0.00008611847,0.00004804086,0.0001159045,0.00008547725,0.0001388421],"category_scores_gemma":[0.003014483,0.0001854537,0.0002463196,0.0005357271,0.0004430369,0.0002268945,0.00005965752,0.0006818158,0.000001474046],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001281043,"about_ca_system_score_gemma":0.0005201747,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001448651,"about_ca_topic_score_gemma":0.00001905031,"domain_scores_codex":[0.9965024,0.0004464057,0.001510574,0.0003823217,0.0007974853,0.0003607885],"domain_scores_gemma":[0.9977209,0.0007987285,0.0002689289,0.0002142774,0.0005182838,0.0004789036],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.3020683,0.001833049,0.03117825,0.00451877,0.001496516,0.03702162,0.05049945,0.00004580338,0.05550753,0.01155305,0.001194597,0.5030831],"study_design_scores_gemma":[0.3964628,0.150442,0.004462553,0.02405226,0.01126566,0.004478198,0.373441,0.01741264,0.002482906,0.007809361,0.005793054,0.001897506],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838306,0.006292302,0.006422039,0.00170689,0.0003876094,0.0008283107,0.00000515118,0.00004768295,0.0004793692],"genre_scores_gemma":[0.9959067,0.00004992588,0.001465957,0.001943174,0.0004879593,0.00003103287,0.000002571434,0.00004298745,0.00006977002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5011856,"threshold_uncertainty_score":0.7562582,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03219892842196121,"score_gpt":0.3543795008478948,"score_spread":0.3221805724259336,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}