{"id":"W4391836009","doi":"10.1016/j.mce.2024.112173","title":"C. elegans insulin-like peptides","year":2024,"lang":"en","type":"article","venue":"Molecular and Cellular Endocrinology","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Caenorhabditis elegans; Insulin; Biology; Insulin receptor; Function (biology); Peptide; Cell biology; Hormone; Gene; Biochemistry; Endocrinology; Insulin resistance","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001861931,0.0006894249,0.0004310589,0.0009102875,0.0006112948,0.0004897439,0.0005514856,0.0007118387,0.004017131],"category_scores_gemma":[0.0001931017,0.0003144566,0.0003670274,0.0004353779,0.0002432261,0.0003471746,0.000511398,0.0007687697,0.004282025],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004202554,"about_ca_system_score_gemma":0.000462742,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001788494,"about_ca_topic_score_gemma":0.0026004,"domain_scores_codex":[0.9998031,0.0000120691,0.00002537961,0.00003772409,0.00009462153,0.00002706426],"domain_scores_gemma":[0.9998872,0.00001439245,0.00002478408,0.00001022427,0.00003201138,0.0000312319],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003557268,0.00009071703,0.0005620549,0.001786195,0.00003427576,0.0006296319,0.00006583705,0.0007089466,0.9311417,0.002462232,0.01643997,0.04572274],"study_design_scores_gemma":[0.0001510197,0.0007417682,0.01098122,0.000644036,0.0001389301,0.001995971,0.00008816106,0.002608386,0.3206784,0.001805349,0.6600127,0.0001539699],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4125196,0.2096196,0.06797625,0.003465997,0.004560439,0.00241528,0.07738952,0.01069116,0.211362],"genre_scores_gemma":[0.5530139,0.1301531,0.1110409,0.00258621,0.0004408681,0.002408321,0.05819009,0.0006736229,0.141493],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004017131,"threshold_uncertainty_score":0.0134387,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006523836560111664,"score_gpt":0.2184566149205744,"score_spread":0.2119327783604627,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}