{"id":"W4391839227","doi":"10.21203/rs.3.rs-3950210/v1","title":"Local Delivery of Accutox® Synergises With Immune-checkpoint Inhibitors at Disrupting Tumor Growth","year":2024,"lang":"en","type":"preprint","venue":"Research Square","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University; Defence Research and Development Canada; Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"","keywords":"Immune system; Cancer research; Immune checkpoint; Medicine; Immunotherapy; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001002388,0.0002759937,0.0002019158,0.0001753706,0.00008458054,0.0001922973,0.0001833542,0.0002849067,0.0036268],"category_scores_gemma":[0.00007878302,0.00007299926,0.0001956838,0.0001059503,0.0001159722,0.0001421361,0.0001244832,0.000327803,0.0006506829],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002316776,"about_ca_system_score_gemma":0.0001764254,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003985646,"about_ca_topic_score_gemma":0.0005988014,"domain_scores_codex":[0.9999307,0.000007709431,0.000006412417,0.00001618708,0.00002201068,0.00001692263],"domain_scores_gemma":[0.9999418,0.00001029766,0.00001930467,0.00000534212,0.00001028838,0.00001296268],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004054456,0.00006298602,0.0001273122,0.0001438807,0.000008778814,0.00004937129,0.000009699983,0.0002081414,0.9942394,0.0001202594,0.0006308906,0.003993815],"study_design_scores_gemma":[0.00002891959,0.0006696914,0.001064231,0.00001053756,0.00001766176,0.0001025139,0.000008563759,0.0005883956,0.9919298,0.00002102675,0.0055541,0.000004612934],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9817092,0.005655973,0.003953291,0.0003091267,0.0001788272,0.000128388,0.001673176,0.0004553646,0.005936624],"genre_scores_gemma":[0.9821429,0.00298476,0.003860331,0.0001869996,0.00004572696,0.0001138377,0.001591256,0.00006754167,0.009006518],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0036268,"threshold_uncertainty_score":0.01213282,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06336038282571765,"score_gpt":0.4122147257744266,"score_spread":0.3488543429487089,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}