{"id":"W4391841087","doi":"10.1186/s40001-024-01711-z","title":"The paradoxical role of cytokines and chemokines at the tumor microenvironment: a comprehensive review","year":2024,"lang":"en","type":"review","venue":"European journal of medical research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":101,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Tumor microenvironment; Chemokine; Immunology; Stromal cell; Cancer; Immune system; Cancer research; Medicine; Cytokine; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.01210956,0.0003190639,0.001399554,0.0001619396,0.0004318712,0.00004726617,0.001757765,0.000145656,0.0006856996],"category_scores_gemma":[0.002273481,0.0001277022,0.0006337801,0.0003141235,0.003001123,0.00002989447,0.00113945,0.003245556,0.0005587901],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006547648,"about_ca_system_score_gemma":0.0004229198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000464219,"about_ca_topic_score_gemma":7.326809e-7,"domain_scores_codex":[0.9865164,0.01056704,0.001503728,0.0002570654,0.0006592,0.0004965395],"domain_scores_gemma":[0.9938984,0.004745592,0.0005915561,0.0005188974,0.0001653634,0.00008019596],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002238082,0.00005378604,3.847233e-7,0.006766066,0.0008038412,0.0002564394,0.00008590367,5.770888e-9,0.0008274473,0.00005939677,0.03615407,0.9547688],"study_design_scores_gemma":[0.000349955,0.0003771069,0.00001531768,0.04847749,0.0004042443,0.005618064,0.0001113586,9.511806e-8,0.0001795163,0.00001667323,0.9443448,0.0001054327],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004087437,0.9954206,6.186714e-7,0.003090899,0.0003918437,0.0004203261,0.00001841277,0.000004776435,0.0002437166],"genre_scores_gemma":[0.0001011917,0.997153,0.000002338002,0.0001749717,0.0001611023,0.000009607518,0.000009047269,0.0000547306,0.002334035],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9546634,"threshold_uncertainty_score":0.9997121,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06873088991512816,"score_gpt":0.3862476197799286,"score_spread":0.3175167298648004,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}