{"id":"W4391845545","doi":"10.1186/s13223-024-00876-w","title":"Immune endotyping and gene expression profile of patients with chronic rhinosinusitis with nasal polyps in the aspirin-exacerbated respiratory disease (AERD) and the non-AERD subgroups","year":2024,"lang":"en","type":"article","venue":"Allergy Asthma and Clinical Immunology","topic":"Sinusitis and nasal conditions","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Iran University of Medical Sciences","keywords":"Nasal polyps; Sinusitis; Medicine; Immunology; Asthma; Aspirin; Immune system; GATA3; Immunoglobulin E; Respiratory disease; Internal medicine; Interleukin 4; Gastroenterology; Biology; Antibody; Gene; Lung; Transcription factor","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001098394,0.0001699499,0.0002502106,0.0004047966,0.0002618788,0.0002136849,0.00007730657,0.000219033,0.0007192193],"category_scores_gemma":[0.0003523451,0.00009194154,0.0001685142,0.0003010747,0.0001842511,0.0002104937,0.0001985326,0.000180432,0.00008987856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001178129,"about_ca_system_score_gemma":0.00008406431,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003957623,"about_ca_topic_score_gemma":0.0006088884,"domain_scores_codex":[0.9998728,0.00001902285,0.00001739103,0.0000405352,0.00002270434,0.00002755974],"domain_scores_gemma":[0.999819,0.00002763959,0.00007773071,0.000008617551,0.00002088611,0.00004622606],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005559666,0.00005214181,0.9890382,0.00001872151,0.00002103423,0.0006054803,0.0001508188,0.0000366946,0.007263343,0.00001521382,0.00003856013,0.002203696],"study_design_scores_gemma":[0.00001140906,0.0002333546,0.9979431,0.000004164704,0.00001606678,0.000990235,0.0002264215,0.0001103402,0.0003075883,0.00001683592,0.0001378595,0.000002581815],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9997197,0.0001000104,0.00002491177,0.000005954981,0.000001605114,0.00000420894,0.00003400054,4.048904e-7,0.000109246],"genre_scores_gemma":[0.9997264,0.00004860349,0.00004933104,0.00001397653,0.000005303263,0.000007967984,0.0000824898,3.237897e-7,0.00006572402],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007192193,"threshold_uncertainty_score":0.002406001,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009449122123313105,"score_gpt":0.2647060260169286,"score_spread":0.2552569038936155,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}