{"id":"W4391848401","doi":"10.1016/j.jcyt.2024.01.013","title":"Source of hematopoietic progenitor cells determines their capacity to generate innate lymphoid cells ex vivo","year":2024,"lang":"en","type":"article","venue":"Cytotherapy","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Amsterdam University Medical Centers; ZonMw; Landsteiner Foundation for Blood Transfusion Research","keywords":"Ex vivo; Progenitor cell; Innate lymphoid cell; Haematopoiesis; Immunology; Stem cell; Bone marrow; Stromal cell; Mucositis; Hematopoietic stem cell transplantation; Cancer research; CD34; Biology; Medicine; In vivo; Innate immune system; Immune system; Radiation therapy; Cell biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002524167,0.0002414696,0.0001854343,0.0002103268,0.0001130667,0.0003457181,0.0001297332,0.0001787994,0.002227951],"category_scores_gemma":[0.0002006432,0.0000922804,0.00009639106,0.0001330544,0.000160236,0.0001920861,0.0002781007,0.0006643545,0.0005862734],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001222978,"about_ca_system_score_gemma":0.0001563396,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001010453,"about_ca_topic_score_gemma":0.0001362676,"domain_scores_codex":[0.9998536,0.00003255051,0.00001444709,0.00002683201,0.0000401975,0.00003238618],"domain_scores_gemma":[0.9998122,0.00007131916,0.00003091053,0.00002268106,0.00002148895,0.00004148726],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001766946,0.00007214607,0.001202951,0.00005906034,0.000003990633,0.0000484564,0.00003224619,0.0001146991,0.9920344,0.0003364938,0.00007935963,0.00583947],"study_design_scores_gemma":[0.00002263328,0.0005281021,0.009103904,0.0000229987,0.00002014371,0.0002892445,0.00004675101,0.00100932,0.983016,0.0001599035,0.005777017,0.000003977756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9812246,0.003587084,0.009908985,0.0001129809,0.00002651028,0.00007678961,0.0005243285,0.0001059935,0.004432668],"genre_scores_gemma":[0.9938785,0.001000052,0.002869573,0.0000515846,0.00001663413,0.00008560465,0.0006731793,0.00002906428,0.001395808],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002227951,"threshold_uncertainty_score":0.007453263,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01661238794148261,"score_gpt":0.2221013918446657,"score_spread":0.2054890039031831,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}