{"id":"W4391848621","doi":"10.1111/tan.15344","title":"Characterization of the novel <i>HLA‐B*57:169</i> allele by next generation sequencing","year":2024,"lang":"en","type":"article","venue":"HLA","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Exon; Genetics; Allele; Human leukocyte antigen; HLA-B; Amino acid substitution; DNA sequencing; Biology; Substitution (logic); Nucleotide; Computational biology; Gene; Molecular biology; Mutation; Antigen; Philosophy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001472983,0.0003049588,0.0002714042,0.0003412477,0.00025483,0.0003531264,0.000258077,0.000514502,0.001829219],"category_scores_gemma":[0.0004176166,0.0001330424,0.0004328821,0.000215736,0.0001952984,0.00007688106,0.0001677717,0.0007207865,0.0008512837],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001523277,"about_ca_system_score_gemma":0.0001952008,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008346126,"about_ca_topic_score_gemma":0.001075173,"domain_scores_codex":[0.9998567,0.00001335862,0.00001638069,0.0000400177,0.00004379838,0.00002979331],"domain_scores_gemma":[0.9997709,0.00005603004,0.00005142395,0.00002470232,0.00004702206,0.00004990192],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000259042,0.00006426908,0.00646003,0.00005346928,0.00003209805,0.003564903,0.00008832896,0.0001315347,0.9811163,0.0002579991,0.0004690152,0.007503098],"study_design_scores_gemma":[0.0002692763,0.0009432137,0.2320001,0.0001532616,0.0004621404,0.05036082,0.0004760892,0.005553681,0.6592973,0.001063502,0.04932876,0.00009183899],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868628,0.0004289901,0.006979349,0.0002714854,0.0001578619,0.0001153659,0.002377818,0.00005582877,0.00275055],"genre_scores_gemma":[0.9781548,0.0003666295,0.01462871,0.0004031598,0.00007021785,0.00008836116,0.00378372,0.00008695524,0.002417475],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001829219,"threshold_uncertainty_score":0.006119311,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0303880723239911,"score_gpt":0.2158216721431591,"score_spread":0.185433599819168,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}