{"id":"W4391848916","doi":"10.1016/j.jcis.2024.02.099","title":"A systematic study of the effect of lipid architecture on cytotoxicity and cellular uptake of cationic cubosomes","year":2024,"lang":"en","type":"article","venue":"Journal of Colloid and Interface Science","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"RMIT University; Council of Scientific and Industrial Research, India; Australian Research Council; Ontario Ministry of Natural Resources and Forestry","keywords":"Cytotoxicity; Cationic polymerization; Chemistry; Biophysics; Nanoparticle; Biochemistry; In vitro; Cell biology; Nanotechnology; Materials science; Organic chemistry; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001773514,0.0001936543,0.0001364512,0.0001122126,0.00008741851,0.0002189355,0.0001161403,0.000145721,0.0003751091],"category_scores_gemma":[0.0003029434,0.00008212519,0.00008357913,0.00009327642,0.0002020462,0.0001602942,0.0001539436,0.0001813161,0.000131816],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002588402,"about_ca_system_score_gemma":0.0002046245,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006271268,"about_ca_topic_score_gemma":0.0006431534,"domain_scores_codex":[0.9998887,0.00002124642,0.00001380478,0.0000271403,0.00003170666,0.00001743756],"domain_scores_gemma":[0.9998021,0.00004770473,0.00006111107,0.00002097882,0.00005573052,0.00001239247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003387406,0.000006291543,0.0001966016,0.00002335633,0.00000186857,0.00001457739,0.00001197892,0.00008989152,0.9989811,0.00002671106,0.000003372577,0.0006103634],"study_design_scores_gemma":[0.000001562916,0.0000818252,0.0008093679,0.00000196549,0.000004898021,0.00003388031,0.000007303816,0.0002875962,0.9985416,0.000005885995,0.0002226179,0.000001521689],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972126,0.0003257918,0.001779613,0.00001553805,0.000002866908,0.0000299287,0.00007631555,0.00001803518,0.0005393216],"genre_scores_gemma":[0.9972981,0.0002919922,0.001880461,0.00001160698,0.000001326333,0.0000250072,0.00008464885,0.000009152928,0.0003977652],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006271268,"threshold_uncertainty_score":0.001877964,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004542568628908589,"score_gpt":0.2498553842390605,"score_spread":0.2453128156101519,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}