{"id":"W4391859080","doi":"10.1039/d3py00939d","title":"Protecting group-free introduction of amino acids to polymers through the aza-Michael reaction","year":2024,"lang":"en","type":"article","venue":"Polymer Chemistry","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Michael reaction; Acrylate; Silicone; Polymer chemistry; Chemistry; Protecting group; Amino acid; Group (periodic table); Polymer; Organic chemistry; Catalysis; Copolymer; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005571385,0.0008965224,0.0003344332,0.0003728842,0.0002813133,0.0002912573,0.0005320914,0.0005466721,0.001306765],"category_scores_gemma":[0.0004201733,0.0003304796,0.0003872952,0.0002819096,0.000475401,0.0004995291,0.0005039316,0.0009037214,0.001022581],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002795908,"about_ca_system_score_gemma":0.0003911408,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002114914,"about_ca_topic_score_gemma":0.0003647105,"domain_scores_codex":[0.999736,0.00004605739,0.00002013137,0.00005552997,0.00009165696,0.00005060065],"domain_scores_gemma":[0.9997615,0.00006982781,0.00007514707,0.0000317343,0.00002316008,0.00003856762],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006702009,0.00001236311,0.00006618328,0.0001181209,0.00001171159,0.0001311748,0.0000373421,0.0001390146,0.9962843,0.000667037,0.00006120836,0.00240451],"study_design_scores_gemma":[0.000004614361,0.00008110137,0.0001609567,0.000003733009,0.000005748583,0.0001425237,0.000003825176,0.0001461262,0.9972275,0.00008862953,0.00212759,0.0000076619],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8813996,0.007922082,0.0983733,0.0004227019,0.0002283215,0.0002361649,0.0007140565,0.001076284,0.00962754],"genre_scores_gemma":[0.958236,0.004538197,0.03056132,0.000101312,0.00005657491,0.0001030323,0.0004386793,0.00007924668,0.005885649],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001306765,"threshold_uncertainty_score":0.004371583,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006439301278418617,"score_gpt":0.2304511970525192,"score_spread":0.2240118957741006,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}