{"id":"W4391873197","doi":"10.1093/jcag/gwad061.050","title":"A50 PRODUCTION OF A PANCREATIC AND INTESTINAL HEPATOCYTE NUCLEAR FACTOR 4A DOUBLE KNOCKOUT MOUSE MODEL TO UNRAVEL NEW MECHANISMS CONTROLLING METABOLISM","year":2024,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Knockout mouse; Hepatocyte; Metabolism; Cell biology; Hepatocyte growth factor; Production (economics); Biology; Chemistry; Biochemistry; Gene; Receptor; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005399504,0.001185797,0.0008242154,0.001951422,0.0004976621,0.0006355818,0.0007357642,0.001178143,0.005713828],"category_scores_gemma":[0.0002317374,0.0006471074,0.001029175,0.0005562137,0.0005941284,0.0007489449,0.0005544495,0.001966987,0.001954943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004620406,"about_ca_system_score_gemma":0.0004230489,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006521753,"about_ca_topic_score_gemma":0.0008653186,"domain_scores_codex":[0.9994082,0.00006836097,0.00007291201,0.0001897954,0.000158551,0.0001021585],"domain_scores_gemma":[0.9994879,0.00003314716,0.0001296104,0.00007918505,0.00006365732,0.0002064891],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003861749,0.0002330837,0.0005004581,0.0001132127,0.00002414131,0.0002484068,0.0000320284,0.0001057561,0.9947589,0.0004546858,0.0003423916,0.002800613],"study_design_scores_gemma":[0.000370888,0.002563387,0.009401866,0.0001116156,0.0002810165,0.003578666,0.0001505785,0.002928382,0.9508994,0.000618285,0.02904357,0.00005237889],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8891159,0.00668355,0.08263291,0.001420735,0.0007228498,0.0009086169,0.007771879,0.002295604,0.008447904],"genre_scores_gemma":[0.8672464,0.007015028,0.06750431,0.0007879708,0.0001788682,0.003032926,0.009234187,0.0007295956,0.04427075],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005713828,"threshold_uncertainty_score":0.01911461,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01715645438273449,"score_gpt":0.235162740619926,"score_spread":0.2180062862371915,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}