{"id":"W4391873380","doi":"10.1093/jcag/gwad061.229","title":"A229 DRUG PERSISTENCE WITH THERAPY OF ADALIMUMAB BIOSIMILAR, IDACIO, IN INFLAMMATORY BOWEL DISEASES","year":2024,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Biosimilar; Adalimumab; Inflammatory Bowel Diseases; Medicine; Persistence (discontinuity); Drug; Inflammatory bowel disease; Pharmacology; Immunology; Internal medicine; Tumor necrosis factor alpha; Disease","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001625817,0.0001503015,0.0004290183,0.00101065,0.0005687355,0.00112392,0.0003257009,0.0003092015,0.00218011],"category_scores_gemma":[0.004068592,0.000109634,0.0005944119,0.00297337,0.0004010692,0.0003931013,0.0004319538,0.000609589,0.0002424859],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001892644,"about_ca_system_score_gemma":0.002875729,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.1665241,"about_ca_topic_score_gemma":0.1521711,"domain_scores_codex":[0.998567,0.0002565159,0.0002196094,0.0002093286,0.0005213625,0.000226135],"domain_scores_gemma":[0.9949568,0.0009487457,0.002590095,0.0002086385,0.000800752,0.0004950627],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000452194,0.00003092682,0.9957876,0.00004133243,0.00006674659,0.00005821497,0.00007734179,0.00005368848,0.00008894153,0.00001792823,0.0001377237,0.003187404],"study_design_scores_gemma":[0.00002359507,0.0001648535,0.998017,0.000028946,0.00008735868,0.0002093343,0.0001904718,0.0003647208,0.00009663769,0.00002380077,0.0007895079,0.000003783241],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963986,0.001098768,0.00009659284,0.00009273744,0.000004409298,0.00002041168,0.001570643,0.000003194933,0.000714675],"genre_scores_gemma":[0.9984856,0.0002128683,0.00007063663,0.00004194776,0.000008173984,0.000009319248,0.000933546,0.000001517167,0.0002363443],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1665241,"threshold_uncertainty_score":0.3311095,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009279761584070055,"score_gpt":0.2237721055565538,"score_spread":0.2144923439724837,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}