{"id":"W4391873380","doi":"10.1093/jcag/gwad061.229","title":"A229 DRUG PERSISTENCE WITH THERAPY OF ADALIMUMAB BIOSIMILAR, IDACIO, IN INFLAMMATORY BOWEL DISEASES","year":2024,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Biosimilar; Adalimumab; Inflammatory Bowel Diseases; Medicine; Persistence (discontinuity); Drug; Inflammatory bowel disease; Pharmacology; Immunology; Internal medicine; Tumor necrosis factor alpha; Disease","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008213288,0.0001120518,0.0003480438,0.000305509,0.00004913638,0.00001240408,0.0003081756,0.0001592417,0.0001261678],"category_scores_gemma":[0.0001570935,0.00007018216,0.0002182162,0.0001547791,0.0002186904,0.00007216111,0.00002235832,0.0003912351,0.000001463854],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003984887,"about_ca_system_score_gemma":0.0004480777,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007212412,"about_ca_topic_score_gemma":0.06102413,"domain_scores_codex":[0.9984313,0.0005799866,0.0005025046,0.0001099417,0.00009404129,0.0002821742],"domain_scores_gemma":[0.9989092,0.0001739234,0.0005286469,0.0001313798,0.000197885,0.00005890704],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006596983,0.00007158586,0.9849221,0.00003315938,0.0006164876,0.00001917831,0.0003232405,0.00003326936,0.005365973,0.0001487639,0.007406214,0.0004003018],"study_design_scores_gemma":[0.002798239,0.001246584,0.9764504,0.000365186,0.0002033234,0.0001226673,0.0003509813,0.00003223468,0.004545685,0.0002855834,0.01348571,0.0001133725],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9800392,0.001574792,0.00001387336,0.01732471,0.0007180818,0.000110379,0.0001064275,0.000003870319,0.0001086103],"genre_scores_gemma":[0.9985752,0.0001753993,0.00009599797,0.00079531,0.00002972603,0.000001324198,0.000001743407,0.000008335926,0.0003170113],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06030289,"threshold_uncertainty_score":0.9561098,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009279761584070055,"score_gpt":0.2237721055565538,"score_spread":0.2144923439724837,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}