{"id":"W4391873688","doi":"10.1093/jcag/gwad061.013","title":"A13 MICROBIOTA FROM PATIENTS WITH INFLAMMATORY BOWEL DISEASE (IBD) INDUCE ALTERED BEHAVIOUR AND VISCERAL HYPERSENSITIVITY IN MICROBIOTA-HUMANIZED MICE","year":2024,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Gastrointestinal motility and disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Inflammatory bowel disease; Gut flora; Humanized mouse; Medicine; Immunology; Disease; Fecal bacteriotherapy; Inflammatory Bowel Diseases; Biology; Pathology; Microbiology; Immune system; Antibiotics; Clostridium difficile","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003124859,0.0008709843,0.0005877169,0.0011277,0.0003802914,0.0004539992,0.0002449607,0.000813157,0.002678404],"category_scores_gemma":[0.0001967827,0.0004539568,0.0008765119,0.0003844616,0.0005175893,0.0003478075,0.000515151,0.001499371,0.0004989804],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003072195,"about_ca_system_score_gemma":0.0002979533,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006135067,"about_ca_topic_score_gemma":0.001060299,"domain_scores_codex":[0.9994548,0.0000836539,0.00005889369,0.0001532097,0.00009464703,0.0001548734],"domain_scores_gemma":[0.9996018,0.00003209201,0.0001146623,0.00003994666,0.00002622065,0.0001853092],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001896128,0.0008912972,0.001356491,0.00006449585,0.00002567193,0.0002262108,0.0000716243,0.00005110105,0.9939263,0.00005047119,0.00008513817,0.001354984],"study_design_scores_gemma":[0.001500307,0.04487323,0.1947471,0.0001760366,0.0003241742,0.006701559,0.001159629,0.00300476,0.7409586,0.0004318683,0.006038044,0.00008476938],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973538,0.0005500047,0.0006972405,0.0001204682,0.00004828856,0.00006134142,0.0006355068,0.0000521468,0.0004812047],"genre_scores_gemma":[0.9926155,0.0008140038,0.002309409,0.0002321989,0.00002967773,0.0001716682,0.001360901,0.00003866293,0.002427981],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002678404,"threshold_uncertainty_score":0.008960128,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004991628310802195,"score_gpt":0.1962087119909495,"score_spread":0.1912170836801473,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}