{"id":"W4391873782","doi":"10.1093/jcag/gwad061.007","title":"A7 CANNABINOID 1 AND 2 RECEPTOR AGONISTS AND MU-OPIOID RECEPTOR AGONISTS SYNERGISTICALLY INHIBIT COLONIC NOCICEPTION DURING ACUTE COLITIS","year":2024,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Gastrointestinal motility and disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Cannabinoid; Nociception; Pharmacology; Receptor; Cannabinoid receptor; Opioid; Chemistry; Cannabinoid receptor type 2; Cannabinoid Receptor Agonists; Colitis; Agonist; Medicine; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000152684,0.000481044,0.0006918883,0.000375713,0.0001486378,0.0002304213,0.0002318502,0.0003228078,0.001791929],"category_scores_gemma":[0.0001717826,0.0001894259,0.0005453707,0.0001711019,0.0002406422,0.0002600761,0.0002553573,0.0009187799,0.0004472528],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001314728,"about_ca_system_score_gemma":0.0002733034,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004271879,"about_ca_topic_score_gemma":0.001308925,"domain_scores_codex":[0.9997434,0.00003562587,0.00002360448,0.00002876304,0.00007164036,0.00009700976],"domain_scores_gemma":[0.9998088,0.00002104369,0.00003778969,0.00001594167,0.00001565926,0.0001008463],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001890215,0.0003517667,0.0002542386,0.0001158436,0.000023901,0.00005611507,0.0000168394,0.00007328625,0.9934734,0.00001942943,0.0001425903,0.003582371],"study_design_scores_gemma":[0.0003343186,0.01960273,0.02760196,0.00006997307,0.0001754437,0.0005640225,0.0001453951,0.001779753,0.9464505,0.00009494789,0.003160047,0.00002101229],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929332,0.003520525,0.00108479,0.0002010706,0.0001395853,0.000053339,0.0002979337,0.00009529911,0.001674349],"genre_scores_gemma":[0.9921176,0.002294162,0.001978709,0.0002018522,0.00007868792,0.0001421902,0.0003469891,0.00001807223,0.002821927],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001791929,"threshold_uncertainty_score":0.005994558,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005023215456638753,"score_gpt":0.221386000924275,"score_spread":0.2163627854676362,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}