{"id":"W4391878131","doi":"10.1101/2024.02.14.580352","title":"Milteforan, a promising veterinary commercial product against feline sporotrichosis","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Azrieli Foundation; Conselho Nacional de Desenvolvimento Científico e Tecnológico; International Development Research Centre; Fundação de Amparo à Pesquisa do Estado de São Paulo; Canadian Institutes of Health Research; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Sporotrichosis; Sporothrix schenckii; Terbinafine; Itraconazole; Sporothrix; Leishmaniasis; Biology; Miltefosine; Medicine; Microbiology; Antifungal; Veterinary medicine; Dermatology; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009501179,0.0002313659,0.0001102227,0.0003155527,0.0001462894,0.0002018577,0.000123927,0.0003150612,0.002565969],"category_scores_gemma":[0.00009209562,0.00003684761,0.0001457691,0.0001140984,0.0001300239,0.0001802432,0.0001242528,0.0002258871,0.000254882],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001417717,"about_ca_system_score_gemma":0.0001464975,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003566009,"about_ca_topic_score_gemma":0.0005541539,"domain_scores_codex":[0.9999738,0.000006435214,0.000001319329,0.000004098961,0.000007504681,0.000006871672],"domain_scores_gemma":[0.9999751,0.000004979959,0.000007330271,0.000001943585,0.000003916288,0.000006832082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007425235,0.0002092673,0.0005727909,0.0002593446,0.00002613471,0.0003106658,0.00003240844,0.0002795985,0.953077,0.0004711236,0.0005604295,0.04345886],"study_design_scores_gemma":[0.0002435558,0.004917694,0.01151387,0.00008900353,0.0001144694,0.002063844,0.00005648524,0.001186052,0.9223818,0.0002828259,0.05713839,0.00001198318],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9636675,0.02398084,0.003723083,0.0010428,0.00008801108,0.0001395223,0.0004186623,0.0001490218,0.006790568],"genre_scores_gemma":[0.9899843,0.003248128,0.003318882,0.0001131242,0.00003276339,0.0000295506,0.0003579728,0.000008773512,0.002906441],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002565969,"threshold_uncertainty_score":0.008584082,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03008017426401846,"score_gpt":0.2691159515088971,"score_spread":0.2390357772448786,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}