{"id":"W4391886355","doi":"10.1093/jcag/gwad061.227","title":"A227 EXPLORING THE ROLE OF MICROBIAL AND GENETIC FACTORS IN DEFINING THE INTESTINAL IMMUNE SYSTEM USING A HUMANIZED GNOTOBIOTIC MOUSE MODEL","year":2024,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; University of Toronto","funders":"","keywords":"Immune system; Humanized mouse; Biology; Microbiology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000832941,0.001132817,0.0005540195,0.001683411,0.0003991258,0.0008479398,0.0006034183,0.001286826,0.003560384],"category_scores_gemma":[0.0003171146,0.000446467,0.0007815314,0.0004239971,0.0009296395,0.000671931,0.0005252513,0.002096307,0.0009690901],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005236923,"about_ca_system_score_gemma":0.0004429729,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006595238,"about_ca_topic_score_gemma":0.0008691442,"domain_scores_codex":[0.9993315,0.0001391721,0.00007647633,0.000180373,0.0001601319,0.0001124003],"domain_scores_gemma":[0.9992386,0.00009413224,0.000247886,0.0001240211,0.00006205791,0.0002332801],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008192147,0.000437749,0.0007530416,0.00007451703,0.00001566194,0.0001882393,0.00003464554,0.0001199593,0.9954523,0.0003174462,0.0001338187,0.001653532],"study_design_scores_gemma":[0.0004426967,0.01047665,0.02397063,0.000117449,0.0001564972,0.003486085,0.0003758486,0.004545244,0.9427937,0.0008160618,0.01276494,0.00005421929],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.979362,0.001685804,0.01302883,0.0005491289,0.0001554034,0.0003415545,0.002443527,0.0003404576,0.00209333],"genre_scores_gemma":[0.9641057,0.001581508,0.02121949,0.0005113711,0.00006077557,0.0009089477,0.002629454,0.0001678845,0.00881479],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003560384,"threshold_uncertainty_score":0.01191068,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01261110873522343,"score_gpt":0.2183303402905996,"score_spread":0.2057192315553762,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}