{"id":"W4391886777","doi":"10.1002/phar.2907","title":"Response to comment on “International consensus recommendations for the use of prolonged‐infusion β‐lactams endorsed by the American College of Clinical Pharmacy (<scp>ACCP</scp>), the British Society for Antimicrobial Chemotherapy (<scp>BSAC</scp>), the Cystic Fibrosis Foundation (<scp>CFF</scp>), the European Society of Clinical Microbiology and Infectious Diseases (<scp>ESCMID</scp>), the Infectious Diseases Society of American (<scp>IDSA</scp>), the Society of Critical Care Medicine (<scp>SCCM</scp>), and the Society of Infectious Diseases Pharmacists”","year":2024,"lang":"en","type":"letter","venue":"Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy","topic":"Antibiotics Pharmacokinetics and Efficacy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Medicine; Pharmacy; Antimicrobial chemotherapy; Antimicrobial; Chemotherapy; Intensive care medicine; Family medicine; Internal medicine; Microbiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01046931,0.001296288,0.002798488,0.00167338,0.002437291,0.003572447,0.005022107,0.03059336,0.04352955],"category_scores_gemma":[0.1030196,0.001290499,0.005168557,0.001617196,0.002384366,0.004312562,0.002936902,0.03702491,0.03793406],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.007684549,"about_ca_system_score_gemma":0.008950758,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01956593,"about_ca_topic_score_gemma":0.01656608,"domain_scores_codex":[0.9911057,0.001679752,0.001808968,0.001067337,0.003463155,0.0008750109],"domain_scores_gemma":[0.9617161,0.01522477,0.003703017,0.001010773,0.01641592,0.001929389],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002197476,0.000002878264,0.00004517661,0.0001057338,0.00001237745,0.00002597158,0.00001965689,0.000007889719,0.0000174003,0.0001695548,0.9987881,0.0007833687],"study_design_scores_gemma":[0.000312148,0.00005787106,0.001241983,0.001512542,0.0001261028,0.0002976847,0.0002317347,0.0001521798,0.0002979068,0.001950217,0.993729,0.00009071158],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0001052689,0.0009492984,0.0001851688,0.8993745,0.09604564,0.00006677109,0.001756189,0.0001848939,0.001332201],"genre_scores_gemma":[0.000973166,0.0008502677,0.0003298838,0.961265,0.03006258,0.0001953236,0.0004551179,0.0001059761,0.005762737],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.04352955,"threshold_uncertainty_score":0.1456208,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04010828054807736,"score_gpt":0.3857887695255814,"score_spread":0.3456804889775041,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}