{"id":"W4391891862","doi":"10.1016/b978-0-323-95672-7.00015-7","title":"Current clinical trials of new therapeutic agents for Huntington's disease","year":2024,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia Hospital; BC Children's Hospital; University of British Columbia","funders":"","keywords":"Disease; Huntington's disease; Current (fluid); Medicine; Clinical trial; Intensive care medicine; Internal medicine; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001429083,0.0005440623,0.0008093852,0.0007015006,0.0002649773,0.001358516,0.001000049,0.001460475,0.03093242],"category_scores_gemma":[0.001065176,0.0001616019,0.0003848981,0.0006173957,0.0005381343,0.001369245,0.0003878551,0.001639439,0.006273757],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006018032,"about_ca_system_score_gemma":0.0007889249,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005232191,"about_ca_topic_score_gemma":0.001858332,"domain_scores_codex":[0.9997665,0.00009046523,0.00002637247,0.0000214485,0.00007236307,0.00002289244],"domain_scores_gemma":[0.9993339,0.0004731538,0.00006590494,0.00002010087,0.00004522178,0.00006160816],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001581404,0.0003032507,0.0001176717,0.002267588,0.00006131779,0.0002014098,0.00007503654,0.0003275138,0.006481714,0.01024066,0.06995761,0.908385],"study_design_scores_gemma":[0.001198032,0.001871706,0.000868202,0.00196139,0.0001506248,0.000941166,0.0000830662,0.0002377227,0.002776638,0.009503427,0.9803857,0.00002232805],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004313059,0.881267,0.002357775,0.009121946,0.001530163,0.0001140125,0.0004432562,0.0001532561,0.1006996],"genre_scores_gemma":[0.0463221,0.8244117,0.006559288,0.01205917,0.002670242,0.0005327128,0.001430924,0.0001019959,0.1059119],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.03093242,"threshold_uncertainty_score":0.1034793,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2421791735885722,"score_gpt":0.4323882185518301,"score_spread":0.1902090449632578,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}