{"id":"W4391971085","doi":"10.1002/ajoc.202400063","title":"Studying the Structure and Evaluating α‐Glucosidase Inhibition of Novel Acetamide Derivatives Incorporating 4‐Ethyl‐4 <i>H</i> ‐1,2,4‐Triazole Starting from 2‐(Naphthalen‐1‐yl)Acetic Acid","year":2024,"lang":"en","type":"article","venue":"Asian Journal of Organic Chemistry","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"OmegaChem (Canada)","funders":"Hercules Foundation","keywords":"Chemistry; Acetamide; Moiety; Thio-; Acarbose; Hydrogen bond; Acetanilide; Stereochemistry; Substituent; Docking (animal); Proton NMR; Triazole; Molecule; Enzyme; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007561521,0.0003139874,0.0001372018,0.0001039357,0.00005837548,0.0001125465,0.000177311,0.000193596,0.0006874428],"category_scores_gemma":[0.00007242562,0.00007585129,0.000153482,0.0001043034,0.00009280813,0.0001255891,0.00007638312,0.0001766949,0.0001857551],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001035249,"about_ca_system_score_gemma":0.0001179337,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005687919,"about_ca_topic_score_gemma":0.0008107114,"domain_scores_codex":[0.9999568,0.000009928256,0.000003623916,0.000006163959,0.00001174569,0.00001164765],"domain_scores_gemma":[0.9999623,0.000004585263,0.00001478951,0.000003326729,0.000008112058,0.000006812789],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005372329,0.00002405979,0.00006126767,0.00003739711,0.000002948188,0.00003181716,0.00000530159,0.0000894222,0.9988212,0.00002477639,0.00001161111,0.0008364553],"study_design_scores_gemma":[0.00001490879,0.001295469,0.001567535,0.00000490762,0.00001408727,0.00007989564,0.00001098442,0.000526687,0.9957277,0.000008161566,0.0007463335,0.00000334065],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995799,0.001298546,0.001317041,0.00002724791,0.00001407191,0.00002556584,0.0001183673,0.00002907956,0.001370959],"genre_scores_gemma":[0.9959792,0.0009694067,0.001706098,0.00002347978,0.000005480492,0.0000226537,0.0001955166,0.000005869334,0.001092287],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006874428,"threshold_uncertainty_score":0.002299726,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02940243320893575,"score_gpt":0.2644157423657133,"score_spread":0.2350133091567775,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}