{"id":"W4391971108","doi":"10.1210/endocr/bqae024","title":"Impact of Exposure to a Mixture of Organophosphate Esters on Adrenal Cell Phenotype, Lipidome, and Function","year":2024,"lang":"en","type":"article","venue":"Endocrinology","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Institute of Population and Public Health; Canadian Institutes of Health Research; McGill University","keywords":"Lipidome; Chemistry; Lipid droplet; Internal medicine; Endocrinology; Organophosphate; Lipotoxicity; Stimulation; Phthalate; Lipid metabolism; Biochemistry; Biology; Pesticide; Medicine; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001381156,0.0003197594,0.0002784846,0.0001602956,0.0001896747,0.0003692847,0.0001391472,0.0002587783,0.001185156],"category_scores_gemma":[0.0001333411,0.0001147168,0.0002158984,0.0001565225,0.0001676599,0.0001410167,0.0002540067,0.0003554391,0.0002158354],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002563413,"about_ca_system_score_gemma":0.0003336937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004553904,"about_ca_topic_score_gemma":0.00617872,"domain_scores_codex":[0.9998114,0.00002455347,0.00001449401,0.00004328321,0.00006597253,0.00004023485],"domain_scores_gemma":[0.9999032,0.00001697958,0.00001728013,0.00001041763,0.00002600529,0.00002611982],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002892148,0.00002986419,0.001064916,0.00003437839,0.00001157976,0.00006645911,0.00002128736,0.00005710957,0.9973081,0.00001097013,0.0000325148,0.001073613],"study_design_scores_gemma":[0.00001703675,0.00114828,0.05937057,0.00001136714,0.00004623796,0.0002443118,0.0002866626,0.000403331,0.9361783,0.0000410658,0.002237936,0.00001495935],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963925,0.001179458,0.0005838702,0.00007335273,0.00002447469,0.00002265314,0.0008132035,0.00001802808,0.0008923988],"genre_scores_gemma":[0.9948483,0.001045933,0.0007568076,0.00007518601,0.000007429075,0.00002972911,0.000751109,0.000008177713,0.002477365],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004553904,"threshold_uncertainty_score":0.00905484,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005665996241123546,"score_gpt":0.233358415904131,"score_spread":0.2276924196630074,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}