{"id":"W4391994071","doi":"10.1242/dev.202217","title":"LiverZap: a chemoptogenetic tool for global and locally restricted hepatocyte ablation to study cellular behaviours in liver regeneration","year":2024,"lang":"en","type":"article","venue":"Development","topic":"Liver physiology and pathology","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; National Institute of Genetics; Novo Nordisk Fonden; Novo Nordisk; Danmarks Grundforskningsfond; European Commission","keywords":"Biology; Regeneration (biology); Hepatocyte; Liver regeneration; Cell biology; Ablation; Development studies; Anatomy; Genetics; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003452826,0.0006885336,0.0003181997,0.0007563715,0.0004152463,0.0003392777,0.0005880982,0.0007060845,0.002825227],"category_scores_gemma":[0.0001369898,0.0004010557,0.0004137519,0.000240203,0.0005816386,0.0004384347,0.0006415109,0.001324065,0.0007970595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005528688,"about_ca_system_score_gemma":0.0005763384,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001410673,"about_ca_topic_score_gemma":0.002531312,"domain_scores_codex":[0.9998068,0.00001909744,0.00001017344,0.00004419622,0.00008236901,0.00003744008],"domain_scores_gemma":[0.9998552,0.00002868252,0.00004660905,0.00001982521,0.0000128256,0.0000367879],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001533548,0.000008912358,0.00004123494,0.00004031044,0.000002757825,0.00003968783,0.00001124759,0.00007857013,0.9977616,0.000289594,0.0001057727,0.001604868],"study_design_scores_gemma":[0.00002024294,0.0001290478,0.0008180144,0.00001349989,0.00001209657,0.0003461134,0.00001037209,0.001271212,0.9896632,0.00009154213,0.007612919,0.00001169132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.5382627,0.006817247,0.425598,0.001269577,0.0003639807,0.001392892,0.003191121,0.006582518,0.01652203],"genre_scores_gemma":[0.781213,0.004754382,0.1890297,0.0004232583,0.00004212021,0.001476586,0.001643096,0.0007875164,0.02063034],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.002825227,"threshold_uncertainty_score":0.00945133,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02416263684316406,"score_gpt":0.2819437211907393,"score_spread":0.2577810843475752,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}