{"id":"W4391994515","doi":"10.1001/jamadermatol.2023.6236","title":"Use of Efficiency Frontiers to Align Prices and Clinical Benefits of Biologic Therapies for Plaque Psoriasis","year":2024,"lang":"en","type":"letter","venue":"JAMA Dermatology","topic":"Health Systems, Economic Evaluations, Quality of Life","field":"Economics, Econometrics and Finance","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Etanercept; Psoriasis; Infliximab; Plaque psoriasis; Psoriasis Area and Severity Index; Biosimilar; Ustekinumab; Internal medicine; Dermatology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.004477766,0.0003066583,0.002629437,0.00078557,0.00006399609,0.00006512309,0.0004027575,0.001425877,0.00003257587],"category_scores_gemma":[0.003931757,0.0003263894,0.0003108279,0.0001628546,0.0002596968,0.000187006,0.0001111932,0.0004760161,0.0001050209],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008885116,"about_ca_system_score_gemma":0.0001348492,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003045953,"about_ca_topic_score_gemma":0.0000420224,"domain_scores_codex":[0.9927713,0.0004047304,0.005482578,0.0008316918,0.00006669625,0.0004430639],"domain_scores_gemma":[0.9910213,0.005164054,0.003065179,0.0005323098,0.000127039,0.00009010898],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003257196,0.00004054563,0.02886814,0.001736176,0.0003840987,0.000002973751,0.000700922,0.0000207461,3.520593e-7,0.01598992,0.9518258,0.000397766],"study_design_scores_gemma":[0.0005854296,0.0002571696,0.006888602,0.0001923736,0.00006200907,0.00003005609,0.0001758674,0.0008386102,0.00001288868,0.008990823,0.9815782,0.0003879848],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.1546177,0.01264304,0.003727929,0.8218577,0.002745948,0.001471437,0.002794807,0.00003931315,0.0001021435],"genre_scores_gemma":[0.02799252,0.003951539,0.03240487,0.9319746,0.002210959,0.0004609114,0.0003887615,0.0001373219,0.0004784815],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1266252,"threshold_uncertainty_score":0.9999188,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3584395629300329,"score_gpt":0.4255275841650145,"score_spread":0.06708802123498159,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}