{"id":"W4392011343","doi":"10.1016/j.ydbio.2024.02.005","title":"Tissue-specific compensatory mechanisms maintain tissue architecture and body size independent of cell size in polyploid zebrafish","year":2024,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Zebrafish Biomedical Research Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of New Brunswick","funders":"Natural Sciences and Engineering Research Council of Canada; New Brunswick Innovation Foundation","keywords":"Biology; Polyploid; Ploidy; Genome size; Zebrafish; Cell size; Cell; Myotome; Cell biology; Vertebrate; Vascular tissue; Anatomy; Genome; Embryo; Genetics; Botany; Embryogenesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001536791,0.0001955646,0.0001548673,0.0003838277,0.0001953768,0.0001827118,0.0002736436,0.000299231,0.001241164],"category_scores_gemma":[0.0002226077,0.0002152066,0.0002788651,0.00009114906,0.0003617392,0.0002946581,0.0004009178,0.000519337,0.0002250395],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005897791,"about_ca_system_score_gemma":0.0003099225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002860845,"about_ca_topic_score_gemma":0.004257551,"domain_scores_codex":[0.9998858,0.000008514547,0.0000143909,0.00003749693,0.00003096547,0.00002280133],"domain_scores_gemma":[0.9997646,0.00002005319,0.00009460363,0.00002780511,0.00002635819,0.00006649972],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005893806,0.000003284822,0.0004426326,0.00001906204,0.000002662145,0.00009089396,0.00003537732,0.00008714876,0.9982523,0.0001876853,0.00003142386,0.000788563],"study_design_scores_gemma":[0.00007668213,0.0007119529,0.1405703,0.00004174562,0.0000721006,0.001258041,0.0002873859,0.004172745,0.846474,0.0007313792,0.00554351,0.0000600973],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954636,0.0003529486,0.002503989,0.0001039517,0.00001323092,0.00001556858,0.0003366973,0.00009075266,0.001119353],"genre_scores_gemma":[0.9929417,0.0002420411,0.002624501,0.00009072066,0.000004676716,0.0000547083,0.000251728,0.00004535166,0.003744456],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002860845,"threshold_uncertainty_score":0.005688369,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006929761305589067,"score_gpt":0.2591162141486014,"score_spread":0.2521864528430123,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}